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Nutrition in Renal Disease

  • Chapter
Contemporary Nephrology

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Abstract

During the past 2 years, there has been an explosion of information attempting to identify the mechanism(s) whereby dietary protein restriction and pharmacologic agents influence progression in experimental models of renal disease. Experimental support for the beneficial effect of exercise on progression, exercise capacity, and intermediary metabolism emphasizes the importance of including exercise in the medical prescription for patients with renal disease. Long-term follow-up of kidney donors indicates that renal function is preserved in kidney donors, tempering concerns that renal dysfunction will progress following uninephrectomy. The utility of dietary protein restriction to reduce proteinuria and raise albumin stores in nephrotic patients has been reported, although its influence on nitrogen or protein balance remains to be determined. Preliminary experience with infusions of naturally occurring isotopes of amino acids to study the adaptive responses of normal subjects to dietary manipulation is available, but there is very little information on the response of uremic patients despite the widespread prescription of low-protein diets. The importance of measuring several indices of nutrition when assessing nutritional status during low-protein diet therapy has recently been emphasized.

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Authors and Affiliations

  1. Renal Division, Emory University School of Medicine, Atlanta, Georgia, 30322, USA

    Bradley J. Maroni & William E. Mitch

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  1. Bradley J. Maroni
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  2. William E. Mitch
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  1. Washington University School of Medicine, St. Louis, Missouri, USA

    Saulo Klahr M.D.

  2. University of Southern California School of Medicine, Los Angeles, California, USA

    Shaul G. Massry M.D.

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© 1989 Plenum Publishing Corporation

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Maroni, B.J., Mitch, W.E. (1989). Nutrition in Renal Disease. In: Klahr, S., Massry, S.G. (eds) Contemporary Nephrology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0829-4_12

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  • DOI: https://doi.org/10.1007/978-1-4613-0829-4_12

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