The Influence of Cutaneous Inputs on the Activity of Neurones in the Substantia Gelatinosa

  • Wilma M. Steedman

Abstract

It is well established that different modalities of sensation are associated with activation of specific types of receptor in the skin. This specificity is preserved in the types of afferent fibre activated and the areas of termination of the central ends of those fibres within the dorsal horn of the spinal cord. Thus in the cat the superficial dorsal horn, and in particular the substantia gelatinosa (lamina II), is the principal area of termination of unmyelinated fibres from cutaneous nociceptors. Intracellular staining of electrophysiologically-characterised C fibres has shown that patterns of terminal arborisation are related to functional attributes (Sugiura et al, 1986). In contrast, the majority of neurones recorded within lamina II are multireceptive and may be excited and inhibited from a variety of cutaneous receptors.

Keywords

Attenuation Morphine Serotonin Hull NMDA 

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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Wilma M. Steedman
    • 1
  1. 1.Department of Preclinical Veterinary Sciences, Royal (Dick) School of Veterinary StudiesUniversity of Edinburgh,Summerhall, EdinburghUK

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