Abstract
During pregnancy, the decidua and placenta synthesise and secrete several protein hormones that have identical or nearly identical chemical and biological properties to protein hormones synthesised and secreted by the pituitary gland and other tissues. For example, human decidual tissue synthesises and releases protein hormones that are identical to pituitary prolactin1 and ovarian relaxin.2 The placenta synthesises and releases hCG and hPL which have striking chemical and biological similarities to LH and to growth hormone and prolactin, respectively.3 Nevertheless, despite the striking similarities between these hormones, the regulation of the synthesis and secretion of the protein hormones from the decidua and placenta is different from that of the pituitary protein hormones. Pituitary prolactin, growth hormone and most protein hormones are stored in large secretory granules, but ultrastructural and biochemical studies indicate that decidual prolactin4 and hPL5 are localised in the post-microsomal supernatants of decidual and placental tissue homogenates.
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References
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© 1989 Plenum Press, New York
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Handwerger, S. et al. (1989). Paracrine and Autocrine Factors Involved in the Regulation of the Release of Human Decidual Prolactin and Human Placental Lactogen. In: Genbačev, O., Klopper, A., Beaconsfield, R. (eds) Placenta as a Model and a Source. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0823-2_13
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DOI: https://doi.org/10.1007/978-1-4613-0823-2_13
Publisher Name: Springer, Boston, MA
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