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Mechanisms Of Altered Growth Regulation In Human Leukemia

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Cell Function and Disease

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Abstract

The process of normal growth requires the orderly occurrence of many events such as interaction of (a) stimulatory growth factor(s) with its (their) own receptors(s), signals transmission throughout the cytoplasm and into the nucleus and finally DNA synthesis and cell division. In the hemopoietic system cell growth is tightly linked to terminal cell differentiation? as soon as the choice between self renewal and lineage commitment is made, terminally differentiated cells are generated throughout a limited number of cells divisions.

Supported by a grant from W.W. Smith Charitable Trust to B.C.

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Authors and Affiliations

  1. Department of Pathology, Temple University Medical School, 3400 N. Broad Street, Philadelphia, PA, 19140, USA

    Bruno Calabretta & Donatella Venturelli

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  1. Bruno Calabretta
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  2. Donatella Venturelli
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Editors and Affiliations

  1. Department of Biochemistry School of Medicine, University of Nuevo Leon, Monterrey, Nuevo Leon, Mexico

    L. E. Cañedo

  2. Magnetic Resonance Unit, University Hospital, Monterrey, Nuevo Leon, Mexico

    L. E. Todd

  3. Lawrence Berkeley Laboratory, University of California, Berkeley, California, USA

    L. Packer

  4. International Biomedical Institute, Bari, Italy

    J. Jaz

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© 1988 Plenum Press, New York

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Calabretta, B., Venturelli, D. (1988). Mechanisms Of Altered Growth Regulation In Human Leukemia. In: Cañedo, L.E., Todd, L.E., Packer, L., Jaz, J. (eds) Cell Function and Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0813-3_3

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  • DOI: https://doi.org/10.1007/978-1-4613-0813-3_3

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