Candidal infections of the gastrointestinal tract are common in patients with acquired immunodeficiency syndrome (AIDS). Oral candidiasis, though not diagnostic of the syndrome, has been shown to carry a poor prognosis in patients in the prodromal stage, called AIDS-related complex (ARC).1–3 In a prospective study of high-risk patients with unexplained oral candidiasis, Klein et al1 found that 59% of these patients acquired a major opportunistic infection or secondary cancer at a median interval of three months. The authors concluded that in high-risk patients, oral candidiasis may represent an intermediate stage in the spectrum of disease that progresses from ARC to AIDS.
KeywordsAcquire Immunodeficiency Syndrome Genital Herpes Sickle Cell Trait Oral Candidiasis Oral Thrush
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