Abstract
In 1985 the enzyme-linked immunosorbent assay (ELISA) to detect antibody to the human immunodeficiency virus (HIV) was licensed by the Food and Drug Administration. Used in conjunction with appropriate confirmatory tests such as the Western blot, it was now possible to identify individuals who had been infected with this virus. The use of these tests was immediately and universally adopted by blood banks in this country. However, their use in the clinical setting was limited by a number of unanswered questions raised by clinicians, advocacy groups, and public health officials. These issues are nearing resolution, and it is now time to place HIV testing in wider clinical use.
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References
Centers for Disease Control: Public Health Service guidelines for counseling and antibody testing to prevent HIV infection and AIDS. MMWR 1987;36:509–515.
DeHovitz JA, Witt MD, Altimont TJ (eds): The AIDS Manual: A Guide for Health Care Administrators. Baltimore, National Health Publishing, 1988.
Wilkerson I: Prenuptial AIDS screening: A strain in Illinois. NY Times, January 26, 1988, p 1.
Meyer KB, Pauker SG: Screening for HIV: Can we afford the false positive rate? NEJM 1987; 317:238–241.
Centers for Disease Control: Update: Serologic testing for antibody to human immunodeficiency virus. MMWR 1988; 36:833–845.
Curran JW, Jaffe HW, Hardy AM, et al: Epidemiology of HIV infection and AIDS in the United States. Science 1988; 239:610–616.
Melbye M, Biggar RJ, Ebbesen P, et al: Long-term seropositivity for human T-lymphotropic virus type III in homosexual men without the acquired immunodeficiency syndrome: Development of immunologic and clinical abnormalities. Ann Intern Med 1986; 104:496–500.
Lane HC, Masur H, Gelmann EP, et al: Correlation between immunologic function and clinical subpopulations of patients with the acquired immune deficiency syndrome. Am J Med 1985; 78:417–422.
Gottleib MS, Knight S, Mitsuyasu R: Prophylaxis of Pneumocystis carinii infection in AIDS with pyrimethamine-sulfadoxine. Lancet 1984; 2:398–399.
Metroka CE, Lange M, Braun N: Successful chemoprophylaxis of Pneumocystis carinii pneumonia with dapsone in patients with AIDS and ARC. Proceedings of the Third International Conference on AIDS. Abstract #THP. 231. Washington, DC, 1987.
Veira J: Fansidar prophylaxis of Pneumocystis carinii pneumonia. Proceedings of the Third International Conference on AIDS. Abstract # TP.221. Washington, DC, 1987.
American Thoracic Society/Centers for Disease Control: Mycobacterioses and the acquired immunodeficiency syndrome. Am Rev Respir Dis 1987; 136:492–496.
Lambert B: One in 61 babies in New York City has AIDS antibodies, study says. NY Times, January 12, 1988, p 1.
Landesman S, Minkoff H, Holman S, et al: Serosurvey of human immune-deficiency virus infection in parturients, JAMA 1987; 285:2701–2703.
Centers for Disease Control: HTLV-III/LAV antibody testing at alternate sites. MMWR 1986; 35:284–287.
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© 1989 Medical Society of the State of New York
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Dehovitz, J.A., Landesman, S.H. (1989). Human immunodeficiency virus antibody testing: Time for clinicians to use it. In: Imperato, P.J. (eds) Acquired Immunodeficiency Syndrome. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0807-2_29
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DOI: https://doi.org/10.1007/978-1-4613-0807-2_29
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