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Modern Concepts in Gastroenterology Volume 2 pp 175–182Cite as

New Therapeutic Approaches to Upper Gastrointestinal Motility Disorders

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Part of the book series: Topics in Gastroenterology ((TGEN))

Abstract

Motility of the gastrointestinal tract has long remained an obscure area of gastroenterological science. During the last decades, however, extensive investigations in animals and humans have led to a better understanding of the physiology of gastrointestinal motility and the pathophysiology and therapeutic approaches to related disorders. This chapter will focus on the motility of the stomach and small bowel.

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References

  1. Collins SM, Valori RM. Disruption of small intestinal migrating myoelectric patterns in human disease states. In: Small Intestinal and Colonic Motility (Poitras P, ed). Proceedings of the first international symposium, Montreal, Jouveinal Lab., 1985, pp. 35–50.

    Google Scholar 

  2. Diamant NE. Neurological control of the IDMC. In: Small Intestinal and Colonic Motility (Poitras P, ed). Proceedings of the first international symposium, Montreal, Jouveinal Lab., 1985, pp. 3–13.

    Google Scholar 

  3. Poitras P. Hormonal control of the IDMC. In: Small Intestinal and Colonic Motility (Poitras P, ed). Proceedings of the first international symposium, Montreal, Jouveinal Lab., 1985, pp. 15–23.

    Google Scholar 

  4. Poitras P. Motilin is a digestive hormone in the dog. Gastroenterology 1984;87:909–913.

    PubMed  CAS  Google Scholar 

  5. You CH, Chey WY, Lee KY. Studies on plasma motilin concentration and interdigestive motility of the duodenum in humans. Gastroenterology 1980;79:62–66.

    PubMed  CAS  Google Scholar 

  6. Janssens J, Van Trappen G, Peeters TL. The activity front of migrating motor complex of the human stomach but not of the small intestine is motilin-dependent. Regul Peptides 1983;6:363–369.

    Article  CAS  Google Scholar 

  7. Meyer JH, Dressman J, Fink A, Amidon G. Effect of size and density on canine gastric emptying of nondigestible solids. Gastroenterology 1985;89:805–813.

    PubMed  CAS  Google Scholar 

  8. Mojaverian P, Ferguson RK, Vlasses PH et al. Estimation of gastric residence terms of the Heidelberg capsule in humans: Effect of varying food composition. Gastroenterology 1985;89:392–397.

    PubMed  CAS  Google Scholar 

  9. Feldman M, Smith HJ, Simon TR. Gastric emptying of solid radiopaque markers: studies in healthy subjects and in diabetic patients. Gastroenterology 1984;87:895–902.

    PubMed  CAS  Google Scholar 

  10. Malagelada JR, Robertson JS, Brown MC et al. Intestinal transit of solid and liquid components of a meal in health. Gastroenterology 1984;87:1255–1263.

    PubMed  CAS  Google Scholar 

  11. Read NW, McFarlane A, Kinsman RI et al. Effect of infusion of nutrients solutions into the ileum on gastrointestinal transit and plasma levels of neurotensin and enteroglucagon. Gastroenterology 1984;86:274–280.

    PubMed  CAS  Google Scholar 

  12. Minami H, McCallum RW. The physiology and pathophysiology of gastric emptying in humans. Gastroenterology 1984;86:1592–1610.

    PubMed  CAS  Google Scholar 

  13. Jian R, Ruskone A, Ducrot F, Chaussade S, Rambaud JC, Bernier JJ. Radionuclide and therapeutic assessment of chronic idiopathic dyspepsia. Gastroenterology 1986;90:1477.

    Google Scholar 

  14. You CH, Lee KY, Chey WY, Menguy R. Electrogastrophic study of patients with unexplained nausea, bloating and vomiting. Gastroenterology 1980;79:311–314.

    PubMed  CAS  Google Scholar 

  15. Malagelada JR, Stanghellini U. Manometric evaluation of functional upper gut symptoms. Gastroenterology 1985;88:1223–1231.

    PubMed  CAS  Google Scholar 

  16. Labo G, Bortolotti M, Bezzadini P, Bonora G, Bersani G. Interdigestive gastroduodenal motility and serum motilin levels in patients with idiopathic delay in gastric emptying. Gastroenterology 1986;90:20–26.

    PubMed  CAS  Google Scholar 

  17. Sninsky CA, Martin JC, Mathias JR. Effect of lidamidine hydrochloride, a proposed α 2-adrenergic agonist, in patients with gastroduodenal motor dysfunction. Gastroenterology 1983;84:1315.

    Google Scholar 

  18. Kumar D, Wingate DL. The irritable bowel syndrome: a paroxysmal motor disorder. Lancet 1985;2:973–977.

    Article  PubMed  CAS  Google Scholar 

  19. Valori RM, Kumar D, Wingate DL. Effect of different types of stress and of prokinetic drugs on the control of the fasting motor complex in humans. Gastroenterology 1986;90:1890–1900.

    PubMed  CAS  Google Scholar 

  20. Janisch HD. A double-blind multi-center trial to compare the efficacy of cisapride and ranitidine in the acute treatment of gastroesophageal reflux disease. Gastroenterology 1986;90:1475.

    Google Scholar 

  21. Camilleri M, Brown ML, Zinsmeister AR, Malagelada JR. Cisapride corrects the impaired small bowel transit time of chyme in chronic intestinal pseudoobstruction. Gastroenterology 1985;88:1340.

    Google Scholar 

  22. Gomme L. Effect of R51619 on chronic constipation. In: Cisapride Investigators Brochure 1983; 20.

    Google Scholar 

  23. Kinsman RI, Read NW. Effect of naloxone on feedback regulation of small bowel transit by fat. Gastroenterology 1984;87:335–337.

    PubMed  CAS  Google Scholar 

  24. Stanghellini V, Malagelada JR, Zinsmeister AR, Go VLW, Kao PC. Stress-induced gastro-duodenal motor disturbances in humans: possible humoral mechanisms. Gastroenterology 1983;85:83–91.

    PubMed  CAS  Google Scholar 

  25. Sarna S, Chey WY, Condon RE, Dodds WJ, Myers T, Chang TM. Cause and effect relationship between motilin and migrating myoelectric complexes. Am J Physiol 1983;245:G277–G289.

    PubMed  CAS  Google Scholar 

  26. Poitras P, Honde C, Havrankova J et al. Effect of trimebutine on intestinal motility and plasma motilin in the dog. Am J Physiol 1988 (in press).

    Google Scholar 

  27. Meshkinpour H, Roberts GS, Sandler R, Snape W, Oren J, Baky SH. Dextromethorphan in treatment of irritable bowel syndrome. Gastroenterology 1985;88:1501.

    Google Scholar 

  28. Schang JC, Devroede G. Beneficial effects of naloxone in a patient with intestinal pseudoobstruction. Am J Gastroenterol 1985;80:407–411.

    PubMed  CAS  Google Scholar 

  29. Kreek MJ, Hanh EF, Schaeffer RA, Fishman J. Naloxone, a specific opioid antagonist, reverses chronic idiopathic constipation. Lancet 1983; 261–262.

    Google Scholar 

  30. Becker JM, Sava P, Kelly KA, Shturman L. Intestinal pacing for canine postgastrectomy dumping. Gastroenterology 1983;84:383–387.

    PubMed  CAS  Google Scholar 

  31. Collin J, Kelly KA, Phillips SF. Increased canine jejunal absorption of water glucose and sodium with intestinal pacing. Am J Dig Dis 1978;23:1121–1123.

    Article  PubMed  CAS  Google Scholar 

  32. Morrison P, Kelly K, Hocking M. Electrical dysrhythmia in the Roux-en-Y jejunal limb and their correction by pacing. Gastroenterology 1985;88:1508.

    Google Scholar 

  33. Lemoyne M, Wassef R, Tasse D, Trudel L, Poitras P. Motilin and the vagus in dogs. Can J Physiol Pharmacol 1984;62:1092–1096.

    Article  PubMed  CAS  Google Scholar 

  34. Thompson DG, Richelson E, Malagelada JR. Perturbation of upper gastrointestinal function by cold stress. Gut 1983;24:277–283.

    Article  PubMed  CAS  Google Scholar 

  35. Talley NJ, Piper DW. Major life event stress and dyspepsia of unknown cause. Gut 1986;27:127–134.

    Article  PubMed  CAS  Google Scholar 

  36. Talley NJ, Fung LH, Gilligan IJ, McNeil D, Piper DW. Association of anxiety, neuroticism and depression with dyspepsia of unknown cause. Gastroenterology 1986;0:886–892.

    CAS  Google Scholar 

  37. Latimer, PR, Malmud LS, Fisher RS. Gastric stases and vomiting: behavioral treatment. Gastroenterology 1982;83:684–688.

    PubMed  CAS  Google Scholar 

  38. Svedlund J, Ottoson JO, Sjodin I, Dotevall G. Controlled study of psychotherapy in irritable bowel syndrome. Lancet 1938;10:589–592.

    Google Scholar 

  39. Devroede G. Irritable bowel syndrome: Clinical and therapeutical aspects. In: Small Intestinal and Colonic Motility (Poitras P, ed). Proceedings of the First International Symposium, Montreal, Jouveinal Lab., 1985, pp. 129–139.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Medicine, University of Montreal, and Hôpital Saint-Luc, H2X 3J4, Montreal, Quebec, Canada

    Pierre Poitras

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  1. Pierre Poitras
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Editor information

Editors and Affiliations

  1. University of Calgary, Calgary, Alberta, Canada

    Eldon Shaffer M.D.

  2. The University of Alberta, Edmonton, Alberta, Canada

    Alan B. R. Thomson M.D., Ph.D.

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© 1989 Plenum Publishing Corporation

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Poitras, P. (1989). New Therapeutic Approaches to Upper Gastrointestinal Motility Disorders. In: Shaffer, E., Thomson, A.B.R. (eds) Modern Concepts in Gastroenterology Volume 2. Topics in Gastroenterology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0781-5_9

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  • DOI: https://doi.org/10.1007/978-1-4613-0781-5_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8079-8

  • Online ISBN: 978-1-4613-0781-5

  • eBook Packages: Springer Book Archive

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