Recent Advances In Dopaminergic Implants
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The first attempts at transplanting neural tissue into brains of experimental animals began nearly 100 years ago. Initially progress was slow and halting, but during the last two decades the tremendous advances in the neurosciences have provided the necessary biochemical methods, histological techniques, and specific toxins with which to produce animal models of neurological disorders and to examine the consequences of attempts at replacing damaged neuronal systems using tissue implants. Perhaps the most spectacular and most promising advances have been related to the dopaminergic systems and Parkinson’s disease treatments.
KeywordsSubstantia Nigra Dopaminergic Neuron Caudate Nucleus Local Cerebral Glucose Utilization Dopamine Receptor Supersensitivity
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