Abstract
Sensitization to nickel and to chromium is very common. Approximately 10% of the female population and a smaller, but increasing number of the male population is hypersensitive to nickel (1.). Chromium is known as the most important cause of occupational contact dermatitis in man, the frequency of which (11% in Europe) is still increasing with the increasing use of chromium containing products in our daily life (2,3.). Despite the high prevalence of nickel and chromium hypersensitivity in the population, cases due to dental treatment with nickel and chromium containing alloys are rare. Until now only a few cases of nickel and chromium hypersensitivity have been reported, but also for gold, palladium, copper, mercury and other metals (4–7). To better understand for pathogenetic and predictive reasons, the mechanism behind metal allergy, there is a need for various studies to explore the immunological aspects of this disease.
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© 1988 Plenum Press, New York
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Vreeburg, K.J.J., de Groot, K., v.d. Burg, C.K.H., Scheper, R.J. (1988). Immunological Aspects of Contact Hypersensitivity to Nickel and Chromium in Dental Alloys. In: Hildebrand, H.F., Champy, M. (eds) Biocompatibility of Co-Cr-Ni Alloys. NATO ASI Series, vol 171. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0757-0_21
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DOI: https://doi.org/10.1007/978-1-4613-0757-0_21
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