New Biochemical Parameters in the Diagnosis of Joint Diseases

  • K. Kleesiek
  • R. Reinards
  • H. Greiling


An important aim in the diagnostic strategy of rheumatic diseases is the differentiation between chronic inflammatory and degenerative joint diseases. In the early phase of chronic joint diseases the separation between rheumatoid arthritis and osteoarthrosis, especially polyarticular osteoarthrosis, might be difficult. In principle osteoarthrosis is characterized by an isolated defect of the cartilage metabolism. Therefore biochemical and immunochemical methods which allow the recognition of pathobiochemical alterations of the osteoarthrotic metabolism in blood are lacking. Also during acute inflammatory phases of osteoarthrosis, no changes of biochemical blood parameters are observed.


Articular Cartilage Synovial Fluid Chondroitin Sulfate Joint Disease Septic Arthritis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • K. Kleesiek
    • 1
  • R. Reinards
    • 2
  • H. Greiling
    • 2
  1. 1.Institute of Laboratory and Transfusion MedicineHeart Center Northrhine-WestfaliaBad OeynhausenGermany
  2. 2.Department of Clinical Chemistry and PathobiochemistryAachen University of TechnologyAachenGermany

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