Abstract
Not long ago a new type of methylase, generation N4-methylcytosine (4mC) in DNA was isolated in our laboratory from Bacillus centrosporus (Janulaitis et al., 1983). At present a number of the 4mC type methylases are isolated (Janulaitis et al., 1984; Butkus et al., 1985; 1987) and a wide spread of N4-methlcytosine in DNA of thermophilic and mesophilic bacteria is well documented (Ehrlich et al., 1985, 1987). Since the two methylated cytosine bases occure in native DNA, a comparison of the effects of N4- and C5-methylation on DNA physico-chemical properties and enzyme action seems to be of great interest.
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© 1988 Plenum Press, New York
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Butkus, V. et al. (1988). The Effects of N4- and C5-Methylati on of Cytosine on DNA Physical Properties and Restriction Endonuclease Action. In: Zelinka, J., Balan, J. (eds) Metabolism and Enzymology of Nucleic Acids. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0749-5_10
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DOI: https://doi.org/10.1007/978-1-4613-0749-5_10
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