An Interaction between Dietary Vanadium and Riboflavin in Chicks
We have reported that the toxic effects of vanadium in chicks can be ameliorated by the inclusion of iron, copper, mercury, and ascorbic acid in the diet, but that zinc was ineffective (1,2,3). These findings lead to the conclusion that there was a reduction-oxidation component in the counteraction of vanadium toxicity and lead to the speculation that components of the diet important in oxidation reactions would also affect vanadium toxicity. We have examined the effect of riboflavin deficiency. A corn-soybean meal basal diet was used in which the riboflavin was omitted from the vitamin mix. The basal diet contained ca. 1.7 mg/kg riboflavin, approximately half the requirement for growth.
KeywordsAscorbic Acid Basal Diet Deficient Animal Ammonium Metavanadate Riboflavin Deficiency
Unable to display preview. Download preview PDF.
- 1.T. L. Blalock and C. H. Hill, Metabolism of Cadmium, Cobalt, Nickel and Vanadium in Iron Deficient Chicks, Fed. Proc. 43, 679 (1984).Google Scholar
- 2.C. H. Hill, Interactions of Copper and Mercury With Vanadate in the Chick, Fed. Proc. 44, 751 (1985).Google Scholar
- 3.C. H. Hill, Studies on the Ameliorating Effect of Ascorbic Acid on Mineral Toxicities in the Chick, J. Nutr. 1009, 84 (1979).Google Scholar