Binding of Zinc to Colloidal Calcium Phosphate in Human and Cow’s Milks
The lower bioavailability of Zn in cow’s milk compared with human milk is well documented. It is generally agreed that this is due to differences in the nature and/or concentrations of Zn-binding ligands in the two milks and in the interactions of Zn with these ligands or their digestion products in the gastrointestinal tract. Lonnerdal et al. (1985) have shown that the bioavailability to rats of the Zn associated with bovine casein micelles is lower than that in human milk. However, the nature of Zn binding in casein micelles is poorly understood. The object of this study was to investigate the distribution of Zn in human and bovine milks and to examine the nature of Zn binding in casein micelles.
KeywordsZinc Filtration EDTA Citrate Spectrophotometry
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