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The Predicament — How should Selenoproteins be Hydrolyzed and Bioavailability Studies with Selenium Conducted?

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Trace Elements in Man and Animals 6
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Abstract

The majority of the selenium (Se) bioavailability studies have been conducted with selenite as the standard.1,2 However, using Se accumulation as the basis, this could lead to erroneous conclusions if the test samples contain selenomethionine (SeMet) as the form of Se. This is demonstrated by a study with rats where Se (0.2 to 4.0 ppm) as either selenite or SeMet was fed to rats (see Figure).

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References

  1. O.A. Levander, Selenium in Biology and Medicine, Third International Symposium, Beijing, PRC, G.F. Combs, J.E. Spallholz, O.A. Levander and J.E. Oldfield, Eds., Avi, Van Nostrand Reinhold Co., New York, N.Y., p. 403.

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  2. A.R. Alexander, P.D. Whanger and L.T. Miller, J. Nutr. 113: 196 (1983).

    PubMed  CAS  Google Scholar 

  3. P.D. Whanger and J.A. Butler. Biol. Trace Element Res. (subm. 1987 ).

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  4. M.A. Beilstein and P.D. Whanger, J. Nutr. 116: 1711 (1986).

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  5. M.G.N. Hartmanis and T.C. Stadman. Proc. Natl. Acad. Sci. 79: 4912 (1982).

    Article  PubMed  CAS  Google Scholar 

  6. J.W. Forstrom, J.J. Zakowski and A.L. Tappel. Biochemistry 17: 2639 (1978).

    Article  PubMed  CAS  Google Scholar 

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© 1988 Plenum Press, New York

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Whanger, P.D. (1988). The Predicament — How should Selenoproteins be Hydrolyzed and Bioavailability Studies with Selenium Conducted?. In: Hurley, L.S., Keen, C.L., Lönnerdal, B., Rucker, R.B. (eds) Trace Elements in Man and Animals 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0723-5_2

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  • DOI: https://doi.org/10.1007/978-1-4613-0723-5_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8050-7

  • Online ISBN: 978-1-4613-0723-5

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