Copper and Molybdenum Levels in Tissues of Hypercuprotic Sheep during and after being Fed Different Levels of Molybdenum
High levels of molybdenum (Mo) fed for short periods of time can reduce the level of accumulated copper (Cu) in the livers of sheep (1). This results in elevated levels of Cu and Mo in plasma and other tissues (2,3), including the liver (4). Such liver Cu levels will not be a reliable indication of the Cu status of the animal since some time is required after withdrawal of Mo to resume “normal” levels. Plasma Cu was found to reach an elevated level within 12 days of feeding Mo and return to normal within a similar period after withdrawal of Mo (5). The effect of high levels of dietary Mo and the withdrawal of the Mo on Cu and Mo levels in plasma and tissues of sheep was investigated. Two sheep breeds which differ in ability to accumulate hepatic Cu were used.
KeywordsLiver Biopsy Kidney Cortex Sheep Breed Similar Period Kidney Liver
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