Undesired Phototoxicity: Cutaneous Reactions to Systemic Drugs

  • Olle Larkö

Abstract

Most clinical photoreactions to systemic drugs are caused by a limited number of drugs. The problem has increased in importance due to the abundant use of solaria. However, surprisingly few reactions have been reported in these situations. The majority of the photo reactions are of the phototoxic type. This article will deal with unintended harmful photobiological effects in conjunction with systemic drug therapy.

Keywords

Penicillin Porphyrine Tetracycline Rosen Cephalosporin 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Addo, H.A., Ferguson, J., Johnson, B.E., Frain-Vell, W., 1982. A study of benoxaprofen-induced photosensitivity. Br J Dermatol 107 (suppl 22):17.Google Scholar
  2. Bjellerup, M., 1986. Tetracycline phototoxicity. An experimental and clinical study. Thesis, Lunds university, Malmö.Google Scholar
  3. Diffey, B.L., Chalmers, R.J.G., Muston, H.L., 1984. Photobiology of amiodarone: preliminary in vitro and in vivo studies. Clin Exp Dermatol 9:248.PubMedCrossRefGoogle Scholar
  4. Halsey, J.P., Cardoe, W., 1982. Benoxaprofen: side-effect profile in 300 patients. Br Med J 284:1365.CrossRefGoogle Scholar
  5. Hoigné,R.,1975. Penicillins, Cephalosporins and tetracyclines. In: Dukes MNG, ed. Side effects of drugs. Amsterdam, Oxford: Excerpta Medica 8:571.Google Scholar
  6. Marx, J.L., Eisenstat, B.A., Gladstein, A.H., 1983. Quinidine photosensitivity. Arch Dermatol 119:39.PubMedCrossRefGoogle Scholar
  7. Möller, H., Rausing A.,1980. Methacycline hyperpigmentation: A five-year follow-up. Acta Derm Venereol (Stockh) 60:495.Google Scholar
  8. Rosén, K.Swanbeck, G.,1982. Phototoxic reactions from some common drugs provoked by a high-intensity UVA lamp. Acta Derm Venereol (Stockh) 62:246.PubMedGoogle Scholar
  9. Roupe, G., Larkö, 0, Ohlsson, S.B., 1987. Amiodarone photoreactions. Acta Derm Venereol (Stockh) 67:76.PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Olle Larkö
    • 1
  1. 1.Department of DermatologySahlgren’s HospitalGöteborgSweden

Personalised recommendations