Adenoviruses

  • Hjordis M. Foy
Chapter

Abstract

Adenoviruses (Ads) derived their name from the fact that they were first isolated from adenoid tissues (tonsils) and have a certain affinity for lymph glands, where they may remain latent for years. There are seven subgenera with 41 species (previously serotypes) (Table 1). Symptoms of infection and epidemiologic patterns vary between subgenera and even for different species. Adenoviruses invade primarily the respiratory and gastrointestinal tracts and the conjunctiva. They may cause a variety of clinical manifestations ranging from pharyngitis to bronchitis, croup, pneumonia, and diarrhea. Some species invade the urinary tract or central nervous system or cause systemic infections. Adenovirus infections are widely distributed and common. Most infections occur in childhood.

Keywords

Hepatitis Influenza Diarrhea Interferon Sewage 

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References

  1. 1.
    Adrian, T., Wigand, R., and Hierholzer, J. C., Immunological and biochemical characterization of human adenoviruses from subgenus B. II. DNA restriction analysis. Arch. Virol 84: 79–89 (1985).CrossRefGoogle Scholar
  2. 2.
    Andiman, W. A., and Miller, G., Persistent infection with adenovirus types 5 and 6 in lymphoid cells from humans and woolly monkeys, J. Infect. Dis. 145: 83–88, (1982).CrossRefGoogle Scholar
  3. 3.
    Aoki, K., Kato, M., Ohtsuka, H., Ishii, K., Nakazono, N., and Harumisawada, Clinical and aetiological study of adenoviral conjunctivitis, with special reference to adenovirus types 4 and 19 infections, Br. J. Ophthalmol. 66: 776–780 (1982).CrossRefGoogle Scholar
  4. 4.
    Arlander, T. R., Pierce, W. E., Edwards, E. A., Peckinpaugh, R. O., and Miller, L. F., IV. An epidemiologic study of respiratory illness patterns in Navy and Marine Corps recruits, Am. J. Public Health 55: 67–80 (1965).CrossRefGoogle Scholar
  5. 5.
    Bahn, C., Swimming bath conjunctivitis, New Orleans Med. Sci. J. 79: 586–590 (1927).Google Scholar
  6. 6.
    Baraff, L. J., Wilkins, J., and Wehrle, P. F., The role of antibiotics, immunizations, and adenoviruses in pertussis, Pediatrics 61: 224–230 (1978).Google Scholar
  7. 7.
    Bell, J. A., Huebner, R. J., Rosen, L., Rowe, W. P., Cole, R. M., Mastrota, F. M., Floyd, T. M., Chanock, R. M., and Shvedoff, R. A., Illness and microbial experiences of nursery children at Junior Village, Am. J. Hyg. 74: 267–292 (1961).Google Scholar
  8. 8.
    Bell, J. A., Rowe, W. P., Engler. J. I., Parrott, R. H., and Huebner, R. J., Pharyngoconjunctival fever: Epidemiological studies of a recently recognized disease entity, J.A.MA. 175: 1083–1092 (1955).Google Scholar
  9. 9.
    Bell, J. A., Rowe, W. P., and Rosen, L., II. Adenoviruses, Am. J. Public Health 52: 902–907 (1962).CrossRefGoogle Scholar
  10. 10.
    Bell, J. A., Ward, T. G., Huebner, R. J., Rowe, W. P., Suskind, R. G., and Paffenbarger, R. S., Jr., Studies of adenoviruses (APC) in volunteers, Am. J. Public Health 46: 1130–1146 (1956).CrossRefGoogle Scholar
  11. 11.
    Bell, S. D., Jr., Rota, T. R., and McComb, D. E., Adenoviruses isolated in Saudi Arabia. III. Six new serotypes, Am. J. Trop. Med. 9: 523–526 (1960).Google Scholar
  12. 12.
    Benyesh-Melnick, M., and Rosenberg, H. S., The isolation of adenovirus type 7 from a fatal case of pneumonia and disseminated disease, J. Pediatr. 64: 83–87 (1964).CrossRefGoogle Scholar
  13. 13.
    Brandt, C. D., Kim, H. W., Jeffries, B. C., Pyles, G., Christmas, E. E., Reid, J. L., Chanock, R. M., and Parrott, R. H., Infections in 18,000 infants and children in a controlled study of respiratory tract disease. II. Variation in adenovirus infections by year and season, Am. J. Epidemiol. 95: 218–227 (1972).Google Scholar
  14. 14.
    Brandt, C. D., Kim, H. W., Rodriguez, W. J., Thomas, L., Yolken, R. H., Arrobio, J. O., Kapikian, A. Z., Parrott, R. H., and Chanock, R. M., Comparison of direct electron microscopy, immune electron microscopy, and rotavirus enzyme-linked immunosorbent assay for detection of gastroenteritis viruses in children, J. Clin. Microbiol. 13: 976–981 (1981).Google Scholar
  15. 15.
    Brandt,C. D.,Kim,H. W.,Vargosko,A. J.,Jeffries,B. C., Arrobio, J. O., Rindge, B., Parrott, R. H., and Chanock, R. M., Infections in 18,000 infants and children in a controlled study of respiratory tract disease. I. Adenovirus pathogenicity in relation to serologic type and illness syndrome, Am. J. Epidemiol. 90: 484–500 (1969).Google Scholar
  16. 16.
    Chanock, R. M., Ludwig, W., Huebner, R. J., Cate, T. R., and Chu, L. W., Immunization by selective infection with type 4 adenovirus grown in human diploid tissue culture. I. Safety and lack of oncogenicity and tests for potency in volunteers, J.A.M.A. 195: 151–158 (1966).CrossRefGoogle Scholar
  17. 17.
    Chany, C., Lepine, P., Lelong, M., Vinh, L. T., Satge, P., and Virat, J., Severe and fatal pneumonia in infants and young children associated with adenovirus infections, Am. J. Hyg. 67: 367–378 (1958).Google Scholar
  18. 18.
    Chiba, S., Nakata, S., Nakamura, I., Taniguchi, K., Urasawa, S., Fujinaga, K., and Nakao, T., Outbreak of infantile gastroenteritis due to type 40 adenovirus, Lancet 2: 954–957 (1983).CrossRefGoogle Scholar
  19. 19.
    Chin-Hsien, T., Adenovirus pneumonia epidemic among Peking infants and pre-school children in 1958, Chin. Med. J. 80: 331 - 339 (1960).Google Scholar
  20. 20.
    Clarke, E. J., Phillips, I. A., and Alexander, E. R., Adenovirus infection in intussusception in children in Taiwan, J.A.M.A. 208: 1671–1674 (1969).CrossRefGoogle Scholar
  21. 21.
    Commission on Acute Respiratory Diseases, Experimental transmission of minor respiratory illness to human volunteers by filter-passing agents. I. Demonstration of two types of illness characterized by long and short incubation periods and different clinical features, J. Clin. Invest. 26: 957–973 (1947).CrossRefGoogle Scholar
  22. 22.
    Connor, J. D., Evidence for an etiologic role of adenoviral infection in pertussis syndrome, N. Engl. J. Med. 283: 390–394 (1970).CrossRefGoogle Scholar
  23. 23.
    Cooney, M. K., Hall, C. E., and Fox, J. P., The Seattle Virus Watch. III. Evaluation of isolation methods and summary of infections detected by virus isolations, Am. J. Epidemiol. 96: 286–305 (1972).Google Scholar
  24. 24.
    Couch, R. B., Cate, T. R., Fleet, W. F., Gerone, P. J., and Knight, V., Aerosol-induced adenoviral illness resembling the naturally occurring illness in military recruits, Am. Rev. Respir. Dis. 93: 529–535 (1966).Google Scholar
  25. 25.
    Couch, R. B., Chanock, R. M., Cate, T. R., Lang, D. J., Knight, V., and Huebner, R. J., Immunization with types 4 and 7 adenovirus by selective infection of the intestinal tract, Am. Rev. Respir. Dis. 88: 394–403 (1963).Google Scholar
  26. 26.
    D’Angelo, L. J., Hierholzer, J. C., Holman, R. C., and Smith, J. D., Epidemic keratoconjunctivitis caused by adenovirus type 8: Epidemiologic and laboratory aspects of a large outbreak, Am. J. Epidemiol. 113: 44–49 (1981).Google Scholar
  27. 27.
    D’Angelo, L. J., Hierholzer, J. C., Keenlyside, R. A., Anderson, L. J., and Martone, W. J., Pharyngoconjunctival fever caused by adenovirus type 4: Report of a swimming pool-related outbreak with recovery of virus from pool water. J. Infect. Dis. 140: 42–47 (1979).CrossRefGoogle Scholar
  28. 28.
    Darougar, S,, Grey, R. H. B., Thaker, U., and McSwiggan, D. A., Clinical and epidemiological features of adenovirus keratoconjunctivitis in London, Br. J. Ophthalmol. 67: 1–7 (1983).CrossRefGoogle Scholar
  29. 29.
    Darougar, S., Walpita, P., Thaker, U., Viswalingam, N., Gardner, L., and McSwiggan, D. A., Adenovirus serotypes isolated from ocular infections in London, Br. J. Ophthalmol. 67: 111–114 (1983).CrossRefGoogle Scholar
  30. 30.
    de Jong, J. C., Wigand, R., Wadell, G., Keller, D., Muzerie, C. J., Wermenbol, A. G., and Schaap, G. J. P., Adenovirus 37: Identification and characterization of a medically important new adenovirus type of subgroup D, J. Med. Virol. 7:105–118(1981).CrossRefGoogle Scholar
  31. 31.
    de Jong, P. J., Valderrama, G., Spigland, I., and Horwitz, M. S., Adenovirus isolates from urine of patients with acquired immunodeficiency syndrome, Lancet 1: 1293–1296 (1983).CrossRefGoogle Scholar
  32. 32.
    Dingle, J., and Langmuir, A. D., Epidemiology of acute respiratory disease in military recruits, Am. Rev. Respir. Dis. 97: 1–65 (1968).Google Scholar
  33. 33.
    Dudding, B. A., Top, F. H., Jr., Winter, P. E., Buescher, E. L., Lamson, T. H., and Leibovitz, A., Acute respiratory disease in military trainees: The adenovirus surveillance program, 1966–1971, Am. J. Epidemiol. 97: 187–198 (1973).Google Scholar
  34. 34.
    Dudding, B. A., Wagner, S. C., Zeller, J. A., Gmelich, J. T., French, G. R., and Top, F. H., Jr., Fatal pneumonia associated with adenovirus type 7 in three military trainees, N. Engl. J. Med. 286: 1289–1292 (1972).CrossRefGoogle Scholar
  35. 35.
    Edmondson, W. P., Purcell, R. H., Gunderfinger, B. F., Love, J. W. P., Ludwing, W., and Chanock, R. M., Immunization by selective infection with type 4 adenovirus grown in human diploid tissue culture. II. Specific protective effect against epidemic disease, J.A.M.A. 195: 159–165 (1966).CrossRefGoogle Scholar
  36. 36.
    Edwards, K. M., Bennett, S. R., Garner, W. L., Bratton, D. L., Glick, A. D., Greene, H. L., and Wright, P. F., Reye’s syndrome associated with adenovirus infections in infants, Am. J. Dis. Child. 139: 343–346 (1985).Google Scholar
  37. 37.
    Enders, J. F., Bell, J. A., Dingle, J. H., Francis, T., Jr., Hilleman, M. R., Huebner, R. J., and Payne, A. M. M., “Adenoviruses”: Group name proposed for new respiratory- tract viruses, Science 124: 119–120 (1956).CrossRefGoogle Scholar
  38. 38.
    Evans, A. S., Latent adenovirus infections of the human respiratory tract, Am. J. Hyg. 67: 256–266 (1958).Google Scholar
  39. 39.
    Evans, A. S., Clinical syndromes in adults caused by respiratory infections, Med. Clin. North Am. 51: 803–818 (1967).Google Scholar
  40. 40.
    Evans, A. S., Cenabre, L., Wanat, J., Richards, V., Neiderman, J. C., and Actis, A., Acute respiratory infections in different ecologic settings. I. Argentine military recruits, Am. Rev. Respir. Dis. 108: 1311–1319 (1973).Google Scholar
  41. 41.
    Evans, A. S., Jeffrey, C., and Niederman, J. C., The risk of acute respiratory infections in two groups of young adults in Colombia, South America: A prospective seroepidemiologic study, Am. J. Epidemiol. 93: 463–471 (1971).Google Scholar
  42. 42.
    Fife, K. H., Ashley, R., Shields, A. F., Curfman, M. F., Salter, D., Meyers, J. D., and Corey, L., Comparison of neutralization and DNA restriction enzyme methods for typing clinical isolates of human adenovirus, J. Clin. Microbiol. 22: 95–100 (1985).Google Scholar
  43. 43.
    Forsyth, B. R., Bloome, H. H., Johnson, K. M., and Chanock, R. M., Etiology of primary atypical pneumonia in a military population, J.A.M.A. 191: 364–369 (1965).Google Scholar
  44. 44.
    Fox, J. P., Brandt, C. D., Wassermann, F. E., Hall, C. E., Spigland, I., Kogon, A., and Elveback, L. R., The Virus Watch Program: A continuing surveillance of viral infections in metropolitan New York families. VI. Observations of adenovirus infections: Virus excretion patterns, antibody response, efficiency of surveillance, patterns of infection and relation to illness, Am. J. Epidemiol. 89: 25–50 (1969).Google Scholar
  45. 45.
    Fox, J. P., Hall, C. E., and Cooney, M. K., The Seattle Virus Watch. VII. Observations of adenovirus infections, Am. J. Epidemiol. 105: 362–386 (1977).Google Scholar
  46. 46.
    Foy, H. M., Cooney, M. K., and Hatlen, J. B., Adenovirus type 3 epidemic associated with intermittent chlorination of a swimming pool, Arch. Environ. Health 17: 795–802 (1968).Google Scholar
  47. 47.
    Foy, H. M., Cooney, M. K., McMahan, R., and Grayston, J. T., Viral and mycoplasmal pneumonia in a prepaid medical care group during an eight-year period. Am. J. Epidemiol. 97: 93–102 (1973).Google Scholar
  48. 48.
    Fuchs, N., and Wigand, R., Virus isolation and titration at 33°C and 37°C, Med. Microbiol. Immunol. 161: 123–126 (1975).CrossRefGoogle Scholar
  49. 49.
    Gardner, P. S., Knox, E. G., Court, S. D. M., and Green, C. A., Virus infection and intussusception in childhood, Br. Med. J. 2: 697–700 (1962).CrossRefGoogle Scholar
  50. 50.
    Glezen, W. P., Wulff, H., Lamb, G. A., Ray, C. G., Chin, T. D. Y., and Wenner, H. A., Patterns of virus infections in families with acute respiratory illnesses, Am. J. Epidemiol. 86: 350–361 (1966).Google Scholar
  51. 51.
    Grayston, J. T., Lashof, J. C., Loosli, C. G., and Johnston, P. B., Adenoviruses. III. Their etiological role in acute respiratory disease in civilian adults, J. Infect. Dis. 103: 93–101 (1958).CrossRefGoogle Scholar
  52. 52.
    Grayston, J. T., Loosli, C. G., Smith, M., McCarthy, M. A., and Johnston, P. B., Adenoviruses. I. The effect of total incubation time in HeLa cell cultures on the isolation rate, J. Infect. Dis. 103: 75–85 (1958).CrossRefGoogle Scholar
  53. 53.
    Grayston, J. T., Yang, Y. F., Johnston, P. B., and Ko, L. S., Epidemic keratoconjunctivitis on Taiwan: Etiological and clinical studies, Am. J. Trop. Med. 13: 492–498 (1964).Google Scholar
  54. 54.
    Green, M., Mackey, J. K., Wold, W. S. M., and Rigden, P., Thirty-one human adenovirus serotypes (Adl-Ad31) form five groups (A-E) based upon DNA genome homologies, Virology 93: 481–492 (1979).CrossRefGoogle Scholar
  55. 55.
    Gutekunst, R. R., and Heggie, A. D., Viremia and viruria in adenovirus infections: Detection in patients with rubella or rubelliform illness, N. Engl. J. Med. 264: 374–378 (1961).CrossRefGoogle Scholar
  56. 56.
    Guyer, B., O’Day, D. M., Hierholzer, J. C., and Schaffner, W., Epidemic keratoconjunctivitis: A community outbreak of mixed adenovirus type 8 and type 19 infection, J. Infect. Dis. 132: 142–150 (1975).CrossRefGoogle Scholar
  57. 57.
    Hall, C. E., Brandt, C. D., Frothingham, T. E., Spigland, I., Cooney, M. K., and Fox, J. P., The Virus Watch Program: A continuing surveillance of viral infections in metropolitan New York families. IX. A comparison of infections with several respiratory pathogens in New York and New Orleans families, Am. J. Epidemiol. 94: 367–385 (1971).Google Scholar
  58. 58.
    Harmon, M. W., and Pawlik, K. M., Enzyme immunoassay for direct detection of influenza type A and adenovirus antigens in clinical specimens, J. Clin. Microbiol. 15: 5–11 (1982).Google Scholar
  59. 59.
    Harnett, G. B., and Newnham, W. A., Isolation of adenovirus type 19 from the male and female genital tracts, Br. J. Vener. Dis. 57: 55–57 (1981).Google Scholar
  60. 60.
    Harris, D. J., Wulff, H., Ray, C. G., Poland, J. D., Chin, T. D. Y., and Wenner, H. A., Viruses and disease. III. An outbreak of adenovirus type 7A in a children’s home, Am. J. Epidemiol. 93: 399–402 (1971).Google Scholar
  61. 61.
    Hierholzer, J. C., and Rodriguez, F. H., Jr., Antigenically intermediate human adenovirus strain associated with conjunctivitis, J. Clin. Microbiol. 13: 395–397 (1981).Google Scholar
  62. 62.
    Hilleman, M. R., Hamparian, V. V., Ketler, A., Reilly, C. M., McClelland, L., Cornfield, D., and Stokes, J., Jr., Acute respiratory illness among children and adults: Field study of contemporary importance of several viruses and appraisal of the literature, J.A.M.A. 180: 445–453 (1962).Google Scholar
  63. 63.
    Hilleman, M. R., and Werner, J. H., Recovery of new agents from patients with acute respiratory illness, Proc. Soc. Exp. Biol. Med. 85: 183–188 (1954).Google Scholar
  64. 64.
    Hogan, M. J., and Crawford, J. W., Epidemic keratoconjunctivitis (superficial punctate keratitis, keratitis sub-epithelialis, keratitis maculosa, keratitis nummularis), Am. J. Ophthalmol. 25: 1059–1078 (1942).Google Scholar
  65. 65.
    Horwitz, M. S., Valderrama, G., Korn, R., and Spigland, I., Adenovirus isolates from the urines of AIDS patients: Characterization of group B recombinants, in: Acquired Immune Deficiency Syndrome: UCLA Symposia on Molecular and Cellular Biology, New Series, Vol. 16 (M. S. Gottlieb and J. E. Groopman, eds.), pp. 187–207, Alan R. Liss, New York, 1984.Google Scholar
  66. 66.
    Hyppia, T., Detection of adenovirus in nasopharyngeal specimens by radioactive and nonradioactive DNA probes, J. Clin. Microbiol. 21: 730–733 (1985).Google Scholar
  67. Jawetz, E., The story of shipyard eye, Br. Med. J 1:873- 878 (1959).Google Scholar
  68. 68.
    Jen, K. F., Tai, Y., Lin, Y. C., and Wang, H. Y., The role of adenovirus in the etiology of infantile pneumonia and pneumonia complicating measles, Chin. Med. J. 81: 141–148 (1962).Google Scholar
  69. 69.
    Jordan, W. S., Jr., The frequency of infection with adenoviruses in a family study population, Ann. N.Y. Acad. Sci. 67: 273–278 (1957).CrossRefGoogle Scholar
  70. 70.
    Kaji, M., Kimura, M., Kamiya, S., Tatewaki, E., Takahashi, T., Nakajima, O., Koga, T., Ishida, S., and Majima, Y., An epidemic of pharyngoconjunctival fever among school children in an elementary school in Fukuoka Prefecture, Kyushu J. Med. Sci. 12: 1–8 (1961).Google Scholar
  71. 71.
    Kasel, J. A., Alford, R. H., Lehrich, J. R., Banks, P. A., Huber, M., and Knight, V., Adenovirus soluble antigens for human immunization, Am. Rev. Respir. Dis. 94: 170–174 (1966).Google Scholar
  72. 72.
    Kelsey, D. S., Adenovirus meningoencephalitis, Pediatrics 61: 291–293 (1978).Google Scholar
  73. 73.
    Kemp, M. C., Hierholzer, J. C., Cabradilla, C. P., and Obueski, J. F., The changing etiology of epidemic keratoconjunctivitis: Antigenic and restriction enzyme analyses of adenovirus types 19 and 37 isolated over a 10-year period, J. Infect. Dis. 148: 24–33 (1983).CrossRefGoogle Scholar
  74. 74.
    Kjellen, L., Zetterberg, B., and Svedmyr, A., An epidemic among Swedish children caused by adenovirus type 3, Acta Paediatr. Scand. 46: 561–568 (1957).CrossRefGoogle Scholar
  75. 75.
    Klenk, E. L., Gwaltney, J. M., and Bass, J. W., Bacteriologically proved pertussis and adenovirus infection, Am. J. Dis. Child. 124: 203–207 (1972).Google Scholar
  76. 76.
    Kloene, W., Bang, F. B., Chakraborty, S. M., Cooper, M. R., Kulemann, H., Ota, M., and Shah, K. V., A two-year respiratory virus survey in four villages in West Bengal, India, Am. J. Epidemiol. 92: 307–320 (1970).Google Scholar
  77. 77.
    Kulcsár, G., Vutskits, Zs., Nász, I., Dán, P., and Léb, J., Viruses isolated from appendicitis cases in childhood, Zentralbl. Bakteriol. I. Abt. Orig. 215: 506–510 (1970).Google Scholar
  78. 78.
    Lang, W. R., Howden, C. W., Laws, J., and Burton, J. F., Bronchopneumonia with serious sequelae in children with evidence of adenovirus type 21 infection, Br. Med. J. 1: 73–79 (1969).CrossRefGoogle Scholar
  79. 79.
    Langmuir, A. D., Jarrett, E. T., and Hollaender, A., Studies of the control of acute respiratory disease among Navy recruits, Am. J. Hyg. 48: 240–251 (1948).Google Scholar
  80. 80.
    Lehane, D. E., Newberg, N. R., and Beam, W. E., Environmental modifications for controlling acute respiratory disease, Am. J. Epidemiol. 99: 139–144 (1974).Google Scholar
  81. 81.
    Loosli, C. G., Lemon, H. M., Robertson, O. H., and Hamburger, M., Transmission and control of respiratory disease in Army barracks, J. Infect. Dis. 90: 153–164 (1952).CrossRefGoogle Scholar
  82. 82.
    Mantyjarvi, R., Adenovirus infections in servicemen in Finland, Ann. Med. Exp. Fenn. 44: 1–43 (1966).Google Scholar
  83. 83.
    McCormick, D. P., Wenzel, R. P., Davies, J. A., and Beam, W. E., Nasal secretion protein responses in patients with wild-type adenovirus disease, Infect. Immun. 6: 282–288 (1972).Google Scholar
  84. 84.
    Miller, L. F., Rytel, M., Pierce, W. E., and Rosenbaum, M. J., Epidemiology of nonbacterial pneumonia among Naval recruits, J.A.M.A. 185: 92–99 (1963).Google Scholar
  85. 85.
    Monto, A. S., Napier, J. A., and Metzner, H. L., The Tecumseh study of respiratory illnesses. I. Plan of study and observations on syndromes of acute respiratory disease, Am. J. Epidemiol. 94: 269–279 (1971).Google Scholar
  86. 86.
    Mueller, R. E., Muldoon, R. L., and Jackson, G. C., Communicability of enteric live adenovirus type 4 vaccine in families. J. Infect. Dis. 119: 60–66 (1969).CrossRefGoogle Scholar
  87. 87.
    Mufson, M. A., Belshe, R. B., Horrigan, T. J., and Zollar, L. M., Cause of acute hemorrhagic cystitis in children, Am. J. Dis. Child. 126: 605–609 (1973).Google Scholar
  88. 88.
    Nahmias, A. J., Griffith, D., and Snitzer, J., Fatal pneumonia associated with adenovirus type 7, Am. J. Dis. Child. 114: 36–41 (1967).Google Scholar
  89. 89.
    Nelson, K. E., Gavitt, F., Batt, M. D., Kallick, C. A., Reddi, K. T.. and Levin, S., The role of adenoviruses in the pertussis syndrome, J. Pediatr. 86: 335–341 (1975).CrossRefGoogle Scholar
  90. 90.
    Numazaki, Y., Kumasaka, T., Yano, N., Yamanaka, M., Miyazawa, T., Takai, S., and Ishida, N., Further study of acute hemorrhagic cystitis due to adenovirus type 11, N. Engl. J. Med. 289: 344–347 (1973).CrossRefGoogle Scholar
  91. 90a.
    Pacini, D. L., Collier, A. M., and Henderson, F. W., Adenovirus infections and respiratory illnesses in children in group day care, J. Infect. Dis. 156: 920–927 (1987).CrossRefGoogle Scholar
  92. 91.
    Paderstein, R., Was ist Schwimmbad-Konjunktivitis? Klin. Monatsbl. Augenheilkd. 72: 634–642 (1925).Google Scholar
  93. 92.
    Parrott, R. H., Rowe, W. P., Huebner, R. J., Bernton, H. W., and McCullough, N. B., Outbreak of febrile pharyngitis and conjunctivitis associated with type 3 adenoidal-pharyngeal-conjunctival virus infection, N. Engl. J. Med. 251: 1087–1090 (1954).CrossRefGoogle Scholar
  94. 93.
    Payne, S. B., Grilli, E. A., Smith, A. J., and Hoskins, T. W., Investigation of an outbreak of adenovirus type 3 infection in a boys’ boarding school, J. Hyg. Camb. 93: 277–283 (1984).CrossRefGoogle Scholar
  95. 94.
    Pierce, W. E., Rosenbaum, M. J., Edwards, E. A., Peckinpaugh, R. O., and Jackson, G. G., Live and inactivated adenovirus vaccines for the prevention of acute respiratory illness in Naval recruits, Am. J. Epidemiol. 87: 237–246 (1968).Google Scholar
  96. 95.
    A preliminary report on effects of routine military inoculations on respiratory illness, Proc. Soc. Exp. Biol. Med. 114:369–372 (1963).,Google Scholar
  97. 96.
    Philipson, L., Peterson, U., and Lindberg, U., Molecular biology of adenoviruses, Virol. Monogr. 14: 1–115 (1975).Google Scholar
  98. 97.
    Rodriguez, W. J., Kim, H. W.. Brandt, C. D., Schwartz, R. H., Gardner, M. K., Jeffries, B., Parrott, R. H., Kaslow, R. A., Smith, J. I., and Tariff, H., Fecal adenoviruses from a longitudinal study of families in metropolitan Washington, D.C.: Laboratory, clinical, and epidemiologic observations, J. Pediatr. 107: 514–520 (1985).CrossRefGoogle Scholar
  99. 98.
    Rose, H. M., Lamson, T. H.. and Buescher, E. L., Adenoviral infection in military recruits: Emergence of type 7 and type 21 infections in recruits immunized with type 4 oral vaccine, Arch. Environ. Health 21: 356–361 (1970).Google Scholar
  100. 99.
    Ross, J. G., Potter, C. W., and Zachary, R. B., Adenovirus infection in association with intussusception in infancy, Lancet 2: 221–223 (1962).CrossRefGoogle Scholar
  101. 100.
    Rowe, W. P., Huebner, R. J., Gilmore, L. K., Parrott, R. H., and Ward, T. G., Isolation of a cytopathogenic agent from human adenoids undergoing spontaneous degeneration in tissue culture, Proc. Soc. Exp. Biol. Med. 84: 570–573 (1953).Google Scholar
  102. 101.
    Sarkkinen, H., Ruuskanen, O., Meurman, O., Puhakka, H., Virolainen, E., and Eskola, J., Identification of respiratory virus antigens in middle ear fluids of children with acute otitis media, J. Infect. Dis. 151: 444–448 (1985).CrossRefGoogle Scholar
  103. 102.
    Schmidt, O. W., Cooney, M. K., and Foy, H. M., Adenovirus-associated virus in adenovirus type 3 conjunctivitis, Infect. Immun. 11: 1362–1370 (1975).Google Scholar
  104. 103.
    Schmitz, H., Wigand, R., and Heinrich, W., Worldwide epidemiology of human adenovirus infections, Am. J. Epidemiol. 117: 455–466 (1983).Google Scholar
  105. 104.
    Schonland, M., Strong, M. L., and Wesley, A., Fatal adenovirus pneumonia: Clinical and pathological features, S. Afr. Med. J. 50: 1748–1751 (1976).Google Scholar
  106. 105.
    Schwartz, A. R., Togo, Y., and Hornick, R. B., Clinical evaluation of live, oral types 1,2, and 5 adenovirus vaccines, Am. Rev. Respir. Dis. 109: 233–238 (1974).Google Scholar
  107. 106.
    Shields, A. F., Hackman. R. C., Fife, K. H., Corey, L., and Meyers, J. D., Adenovirus infections in patients undergoing bone-marrow transplantation, N. Engl. J. Med. 312: 529–533 (1985).CrossRefGoogle Scholar
  108. 107.
    Simila, S., Ylikorkala, O., and Wasz-Hockert, O., Type 7 adenovirus pneumonia, J. Pediatr. 79: 605–611 (1971).CrossRefGoogle Scholar
  109. 108.
    Smith, T. J., Buescher, E. L., Top, F. H., Jr., Altemeier, W. A., and McCown, J. M., Experimental respiratory infection with type 4 adenovirus vaccine in volunteers: Clinical and immunological responses, J. Infect. Dis. 122: 239–248 (1970).CrossRefGoogle Scholar
  110. 109.
    Sprague, J. B., Hierholzer. J. C., Currier, R. W. II, Hattwich, M. A. W., and Smith, M. D., Epidemic keratoconjunctivitis: A severe industrial outbreak due to adenovirus type 8, N. Engl. J. Med. 289: 1341–1346 (1973).CrossRefGoogle Scholar
  111. 110.
    Stalder, H., Hierholzer, J. C., and Oxman, M. N., New human adenovirus (candidate adenovirus type 35) causing fatal disseminated infection in a renal transplant recipient, J. Clin. Microbiol. 6: 257–265 (1977).Google Scholar
  112. 111.
    Stanley, E. D., and Jackson, G. G., Spread of enteric live adenovirus type 4 vaccine in married couples, J. Infect. Dis. 119: 51–59 (1969).CrossRefGoogle Scholar
  113. 112.
    Sterner, G., Adenovirus infection in childhood: An epidemiological and clinical survey among Swedish children, Acta Paediatr. Scand. [Suppl.] 142: 1–30 (1962).Google Scholar
  114. 113.
    Straube, R. C., Thompson. M. A., Van Dyke, R. B., Wadell, G., Connor, J. D., Wingard, D., and Spector, S. A., Adenovirus type 7b in a children’s hospital, J. Infect. Dis. 147: 814–819 (1983).CrossRefGoogle Scholar
  115. 114.
    Sutton, R. N. P., Pullen, H. J. M., Blackledge, P., Brown, E. H., Sinclair, L., and Swift, P. N., Adenovirus type 7: 1971-74, Lancet 2: 987–991 (1976).CrossRefGoogle Scholar
  116. 115.
    Svartz-Malmberg, G., and Germanis, M., Adenovirus type 8-associated keratoconjunctivitis: Hospital infections and secondary spread in Stockholm, 1967, Scand J. Infect. Dis. 1: 161–168 (1969).Google Scholar
  117. 116.
    Tai, F. H., and Grayston, J. T., Adenovirus neutralizing antibodies in persons on Taiwan, Proc. Soc. Exp. Biol. Med. 109: 881–884 (1962).Google Scholar
  118. 117.
    Tai, F. H., Grayston, J. T., Johnson, P. B., and Wooldridge, R. L., Adenovirus infections in Chinese Army recruits on Taiwan, J. Infect. Dis. 107: 160–164 (1960).CrossRefGoogle Scholar
  119. 118.
    Top, F. H., Jr., Control of adenovirus acute respiratory disease in U.S. Army trainees, Yale J. Biol. Med. 48: 185–195 (1975).Google Scholar
  120. 119.
    Top, F. H., Jr., Grossman, R. A., Bartelloni, P. J., Segal, H. E., Dudding, B. A., Russell, P. K., and Buescher, E. L., Immunization with live types 7 and 4 adenovirus vaccines. I. Safety, infectivity, and potency of adenovirus type 7 vaccine in humans, J. Infect. Dis. 124: 148–154 (1971).CrossRefGoogle Scholar
  121. 120.
    Uhnoo, I., Wadell, G., Svensson, L., and Johansson, M. E., Importance of enteric adenoviruses 40 and 41 in acute gastroenteritis in infants and young children, J. Clin. Microbiol. 20: 365–372 (1984).Google Scholar
  122. 121.
    VanDerVeen, J., The role of adenoviruses in respiratory disease, Am. Rev. Respir. Dis. 88: 167–180 (1963).Google Scholar
  123. 122.
    Vastine, D. W., West, C. E., Yamashiroya, H., Smith, R., Saxtan, D. D., Gieser, D. I., and Mufson, M. A., Simultaneous nosocomial and community outbreak of epidemic keratoconjunctivitis with types 8 and 19 adenovirus, Trans. Am. Acad. Ophthalmol. Otolaryngol 81:OP826–OP840 (1976).Google Scholar
  124. 123.
    Vihma, L., Surveillance of acute viral respiratory disease in children, Acta Paediatr. Scand. [Suppl.] 192: 8–52 (1969).Google Scholar
  125. 124.
    Virtanen, M., Palva, A., Laaksonen, M., Halonen, P., Soderlund, H., and Ranki, M., Novel test for rapid viral diagnosis: Detection of adenovirus in nasopharyngeal mucus aspirates by means of nucleic-acid sandwich hybridisation, Lancet 1: 381–383 (1983).CrossRefGoogle Scholar
  126. 125.
    Wadell, G., Molecular epidemiology of human adenoviruses, Curr. Top. Microbiol. Immunol. 110: 191–220 (1984).Google Scholar
  127. 126.
    Wadell, G., Cooney, M. K., da Costa Linhares, A., de Silva, L., Kennett, M. L., Kono, R., Ren, G.-F., Lindman, K., Nascimento, J. P., Schoub, B. D., and Smith, C. D., Molecular epidemiology of adenoviruses: Global distribution of adenovirus 7 genome types, J. Clin. Microbiol. 21: 403–408 (1985).Google Scholar
  128. 127.
    Wang, S. S., and Feldman, H. A., Pharyngeal isolations of adenovirus 31 from a family population, Am. J. Epidemiol. 104: 272–277 (1976).Google Scholar
  129. 128.
    Warner, J. O., and Marshall, W. C., Crippling lung disease after measles and adenovirus infection, Br. J. Dis. Chest 70: 89–94 (1976).CrossRefGoogle Scholar
  130. 129.
    Wenman, W. M., Pagtakhan, R. D., Reed, M. H., Chernick, V., and Albritton, W., Adenovirus bronchiolitis in Manitoba. Epidemiologic, clinical, and radiologic features, Chest 81: 605–609 (1982).CrossRefGoogle Scholar
  131. 130.
    Wenner, H. A., Beran, G. W., Weston, J., and Chin, T. D. Y., with collaboration of Anderson, N. W., and Goldsmith, R., The epidemiology of acute respiratory illness. I. Observations on adenovirus infections prevailing in a group of families, J. Infect. Dis. 101: 275–286 (1957).CrossRefGoogle Scholar
  132. 131.
    Wigand, R., Baumeister, H. G., Maass, G., Kuhn, J., and Hammer, H. J., Isolation and identification of enteric adenoviruses, J. Med. Virol. 11: 233–240 (1983).CrossRefGoogle Scholar
  133. 132.
    Wigand, R., and Schulz, R., Laboratoriumspraxis be Adenoviren. II. Empfindlichkeit verschiedener Zellkulturen bei Endpunkttitration, Zentralbl. Bakteriol. Parasitenkd. Infek- tionskr. Abt. 1 Orig. Reihe A 231: 31–41 (1975).Google Scholar
  134. 133.
    Wold, W. S. M., Mackey, J. K., Rigden, P., and Green, M., Analysis of human cancer DNA’s for DNA sequences of human adenovirus serotypes 3,7,11,14,16. and 21 in Group B, Cancer Res 39: 3479–3484 (1979).Google Scholar
  135. 134.
    Yolken, R. H., and Franklin, C. C., Gastrointestinal adenovirus: An important cause of morbidity in patients with necrotizing enterocolitis and gastrointestinal surgery, Pediatr. Infect. Dis. 4: 42–41 (1985).CrossRefGoogle Scholar
  136. 135.
    Yolken, R. H., Lawrence, F., Leister, F., Tariff, H. E., and Strauss, S. E., Gastroenteritis associated with enteric type adenovirus in hospitalized infants, J. Pediatr. 101: 21–26 (1982).CrossRefGoogle Scholar
  137. 136.
    Zahradnik, J. M., Spencer, M. J., and Porter, D. D., Adenovirus infection in the immunocompromised patient, Am. J. Med. 68: 725–732 (1980).CrossRefGoogle Scholar
  138. 137.
    Zweighaft, R. M., Hierholzer, J. C., and Bryan, J. A., Epidemic keratoconjunctivitis at a Vietnamese refugee camp in Florida, Am. J. Epidemiol. 106: 399–407 (1977).Google Scholar

Copyright information

© Plenum Publishing Corporation 1989

Authors and Affiliations

  • Hjordis M. Foy
    • 1
  1. 1.Department of Epidemiology, School of Public Health and Community MedicineUniversity of WashingtonSeattleUSA

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