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Nephrolithiasis and Nephrocalcinosis

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Therapy of Renal Diseases and Related Disorders

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Abstract

From time to time, in most people, the urine separates into a solid and liquid phase. Unlike birds, which regularly produce a semisolid urine, all mammals have renal tubules and urinary collecting systems whose lumens are narrow and easily obstructed. As long as the solid phase in urine consists of very tiny particles, 0.1 to 10 microns in diameter, phase separation is asymptomatic. Larger particles can block tubule lumens or may adhere to papillary surfaces. Once anchored, a particle can then grow, until its dimensions become similar in magnitude to those of the urinary tract, i.e., millimeters to centimeters in diameter. Then, it can cause clinical disease.

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Authors
  1. Joan H. Parks
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  2. Fredric L. Coe
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Editors and Affiliations

  1. Baylor College of Medicine, The Methodist Hospital, Houston, Texas, USA

    Wadi N. Suki

  2. Division of Nephrology, University of Southern California, Los Angeles, California, USA

    Shaul G. Massry

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© 1991 Kluwer Academic Publishers

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Parks, J.H., Coe, F.L. (1991). Nephrolithiasis and Nephrocalcinosis. In: Suki, W.N., Massry, S.G. (eds) Therapy of Renal Diseases and Related Disorders. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0689-4_8

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  • DOI: https://doi.org/10.1007/978-1-4613-0689-4_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8027-9

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