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Edematous States

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Therapy of Renal Diseases and Related Disorders

Abstract

Except when edema is due to local phenomena such as obstruction to venous flow from a thrombus or an inflammatory reaction from infection, the final common pathway responsible for edema formation is retention of salt and water by the kidney. Whether responding appropriately to the patient’s condition as in hypovolemic shock, or in a counterproductive manner, as in congestive heart failure, the kidney’s attempt to preserve body volume results from its perception of a reduction in vascular filling in the arterial circuit. Accordingly, the first consideration in treatment of edema is correction of the underlying disorder, if that can be achieved. When the deranged physiology is irreversible, the mainstays of therapy are a reduction in the salt content of the diet and the administration of diuretic agents. The diuretics currently available share the capability of impairing sodium chloride or bicarbonate reabsorption at one or more sites along the tubular system.

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Authors
  1. Arthur Greenberg
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  2. Jules B. Puschett
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Editors and Affiliations

  1. Baylor College of Medicine, The Methodist Hospital, Houston, Texas, USA

    Wadi N. Suki

  2. Division of Nephrology, University of Southern California, Los Angeles, California, USA

    Shaul G. Massry

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© 1991 Kluwer Academic Publishers

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Greenberg, A., Puschett, J.B. (1991). Edematous States. In: Suki, W.N., Massry, S.G. (eds) Therapy of Renal Diseases and Related Disorders. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0689-4_3

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  • DOI: https://doi.org/10.1007/978-1-4613-0689-4_3

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