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Mixed Acid-Base Disorders

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Therapy of Renal Diseases and Related Disorders

Abstract

Virtually all recent discussions of the diagnosis and management of mixed acid-base disturbances have focused exclusively on the acid-base disorders per se and have relegated the patient and the clinical setting to a subordinate position. In the 1980s several excellent reviews utilizing primarily a laboratory approach have appeared (1–3). In this laboratory-dominated approach, the acid-base data first are examined to determine whether they are consistent with any of the simple acid-base disorders; if the acid-base data do not fit, and assuming that they reflect a steady state, one can confidently conclude that a mixed acid-base disturbance is present (4). For instance, in a patient with a plasma bicarbonate concentration of 8mEq/l, the finding of a PaCO2 level substantially greater than the value anticipated for simple metabolic acidosis establishes the presence of a concomitant element of respiratory acidosis and thus the presence of a mixed acid-base disorder.

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Authors
  1. John T. Harrington
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  2. Nicolaos E. Madias
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Editor information

Editors and Affiliations

  1. Baylor College of Medicine, The Methodist Hospital, Houston, Texas, USA

    Wadi N. Suki

  2. Division of Nephrology, University of Southern California, Los Angeles, California, USA

    Shaul G. Massry

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© 1991 Kluwer Academic Publishers

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Harrington, J.T., Madias, N.E. (1991). Mixed Acid-Base Disorders. In: Suki, W.N., Massry, S.G. (eds) Therapy of Renal Diseases and Related Disorders. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0689-4_14

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  • DOI: https://doi.org/10.1007/978-1-4613-0689-4_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8027-9

  • Online ISBN: 978-1-4613-0689-4

  • eBook Packages: Springer Book Archive

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