Abstract
The possible central and spinal mechanisms involved in the transmission of the pain of reflex sympathetic dystrophy (USD) are discussed in detail in this volume. This study is designed to investigate the possible mechanisms involved in the transmission of pain ofRSD at the postganglionic synapse. Guanethidine has been used successfully to treat the pain of RSD as described by Hannington-Kiff (Chapter 12) and (1). This pain relief has been shown to be associated with sympathetic blockade as measured by an increase in skin blood flow, and abolition of the vasoconstrictor ice response (2). Thus the pain relief achieved with this technique is believed, in part, to be a result of sympathetic blockade at the postganglionic synapse, indicating a possible role for the synapse in pain transmission.
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References
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© 1990 Kluwer Academic Publishers
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Glynn, C.J., Jones, P.C. (1990). An Investigation of the Role of Clonidine in the Treatment of Reflex Sympathetic Dystrophy. In: Stanton-Hicks, M., Jänig, W., Boas, R.A. (eds) Reflex Sympathetic Dystrophy. Current Management of Pain, vol 7. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0685-6_19
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DOI: https://doi.org/10.1007/978-1-4613-0685-6_19
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-8026-2
Online ISBN: 978-1-4613-0685-6
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