Abstract
A spontaneous release of a DNA-containing complex by human lymphocytes has been reported (Anker et al., 1975). The release process was unrelated to cell death and the released DNA consists of newly synthesized DNA. Possibly, part of the human blood plasma DNA represents the DNA released by lymphocytes. It was shown in the work by Anker et al., (1984), that the purified DNA released by antigen stimulated human lymphocytes, when injected into the nude mice is capable of inducing the formation of specific antibodies expressing human characteristics. In the present paper we attempt to show by the technique of the Southern blot analysis that extracellular lymphocyte and human blood plasma DNA contain molecules homologous to the human Ck fragment of the Ig gene.
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© 1990 Plenum Press, New York
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Vasyukhin, V.I., Lipskaya, L.A., Tsvetkov, A.G., Podgornaya, O.I. (1990). The Extracellular Lymphocyte and Blood Plasma DNAs Contain the Discrete Size Molecules Homologous to the Ck Fragment of the Ig Gene. In: Harris, J.R., Zbarsky, I.B. (eds) Nuclear Structure and Function. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0667-2_8
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DOI: https://doi.org/10.1007/978-1-4613-0667-2_8
Publisher Name: Springer, Boston, MA
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