Rat DNA Fingerprinting for Rattus Norvegicus: A New Approach in Genetic Analysis

  • P. L. Ivanov
  • A. P. Ryskov

Abstract

Recent findings with highly effective DNA probes for RFLP testing (of hypervariable minisatellite DNA type) has led to the invention of DNA fingerprinting — the new technique of great value for individual identification, establishing biological kinship and studies in population genetics (Jeffreys et at., 1985a; Jeffreys et al., 1985b: Vassart et al., 1987). More recently, we have demonstrated a potential range of M13 phage DNA applications as a probe for DNA fingerprinting of organisms of different taxonomic groups including animals, plants and microorganisms, specifically for the determination of species and inbred lines, stock, variety and strain distinction (Ryskov et al., 1988). We anticipate now that the DNA fingerprinting procedure with M13 phage DNA as a probe will make it possible to realize some new approach in genetic analysis, by establishing whether or not a particular locus is associated with the inheritance of genetic disease (Lewin, 1986).

Keywords

Agarose Electrophoresis Lewin 

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References

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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • P. L. Ivanov
    • 1
  • A. P. Ryskov
    • 1
  1. 1.Institute of Molecular BiologyUSSR Acad. of SciencesMoscowUSSR

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