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The Study of the Influence of cis-Regulatory Sequences and trans-Regulatory Factors of Eucaryotes on CAT Gene Expression in X. Laevis Oocytes

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Nuclear Structure and Function

Abstract

The specificity of expression of eucaryotic genes depends on various cis- and trans-regulatory sequences and factors. The specificity of expression of bovine casein genes has long been a question of intensive interest. A convenient approach to the study of functional sites of a gene is the use of transformation of animal embryos or cells in vitro. But the question is to move forward more quickly than through transgenic animals. The study of gene regulation of mammary glands also needs a simple model. One possible model — Xenopus laevis oocytes, has been used recently to study factors involved in immunoglobulin gene expression (Sweeney and Old, 1988).

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© 1990 Plenum Press, New York

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Korzh, V.P., Kazansky, A.V., Sleptsova, I.L., Gorodetsky, S.I. (1990). The Study of the Influence of cis-Regulatory Sequences and trans-Regulatory Factors of Eucaryotes on CAT Gene Expression in X. Laevis Oocytes. In: Harris, J.R., Zbarsky, I.B. (eds) Nuclear Structure and Function. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0667-2_21

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  • DOI: https://doi.org/10.1007/978-1-4613-0667-2_21

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-7918-1

  • Online ISBN: 978-1-4613-0667-2

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