The Diagnosis of Alzheimer’s Disease

  • Robert A. Murden
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 282)


The diagnosis of Alzheimer’s Disease has traditionally been a diagnosis of exclusion. Although there is some modestly promising research on diagnostic testing in Alzheimer’s, this remains the standard currently, although clinical patterning can be useful additional evidence. This discussion will focus on this traditional diagnosis of exclusion in the following four-step approach. The first step is to ensure that the patient does, indeed, have dementia. The second step is to review the differential diagnosis of dementia and examine for all of the causes other than Alzheimer’s. The third step is to decide if the clinical presentation of the patient under consideration is consistent with one of the several clinical patterns of Alzheimer’s. The fourth step is to avoid certain pitfalls of diagnosis. These steps shall be discussed in detail in the order noted above.


Normal Pressure Hydrocephalus Alcoholic Dementia Mental Status Change Chronic Meningitis Standardize Neuropsychological Test 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Robert A. Murden
    • 1
  1. 1.Department of MedicineUniversity of Kansas Medical CenterKansas CityUSA

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