Abstract
Oral, vaginal and oesophageal candidosis occur commonly in patients with HIV infection. The incidence of oesophageal candidosis varies between subgroups of the HIV-infected population, indicating that factors more complex than the presence or absence of HIV infection determine the pathogenic status of Candida. Almost all Candida infections in AIDS are caused by the species C. albicans. Some surveys, but not all, show an increased prevalence of C. albicans serotype B strains in AIDS patients. The possibility that the immunosuppression and protracted antifungal chemotherapy associated with HIV infection may create a selective pressure for evolution of unusual C. albicans strains is supported by the finding of unusually closely related DNA types among four of nine AIDS patients in one survey.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Brawner, D.T., and Cutler, J.E., 1989, Oral Candida albicans isolates from nonhospitalized normal carriers, immunocompetent hospitalized patients, and immunocompromised patients with or without acquired immunodeficiency syndrome, J. Clin. Microbiol., 27:1335.
Drouhet, E., Mercier-Soucy, L., and Montplaisir, S., 1975, Sensibilité et résistance des levures pathogènes avec 5-fluoropyrimidines, Ann. Microbiol., 126B:25.
Drouhet, E., Dupont, B., Improvisi, L., Lesourd, M., and Provost, M.C., 1989, La cilofungine (LY121019), nouvel antifongique lipopolypeptidique agissant sur la paroi fongique. Activité in vitro sur les levures, Bull. Soc. Fr. Mycol. Med., 18:31.
Korting, H.C., Ollert, M., Georgii, A., and Froeschl, M., 1988, In-vitro susceptibilities and biotypes of Candida albicans isolates from the oral cavities of patients infected with human immunodeficiency virus, J. Clin. Microbiol., 26:2626.
Matthews, R., Burnie, J., Smith, D., Clark, I., Midgley, J., Connolly, M., and Gazzard, B., 1988, Candida and AIDS: evidence for protective antibody, Lancet, 2:263.
Odds, F.C., 1988, “Candida and candidosis”, 2nd edition, Bailliere Tindall, London.
Penali, L.K., Kone, M., Codo-Agbo, Faye-Kette, H., Kouassi, M.T., Boue Tan, A., and Kouakou, B., 1989, Sensibilité aux antifongiques des sérotypes de Candida albicans isolaés à Abidjan (Côte d’Ivoire), Bull. Soc. Fr. Mycol. Med., 18:371.
Scherer, S., and Stevens, D.A., 1988, A Candida albicans dispersed, repeated gene family and its epidemiologic application, Proc. Nat. Acad. Sci. USA, 85: 1452.
Schmid, J., Voss, E., and Soll, D.R., 1990, Computer-assisted methods for assessing strain relatedness in C. albicans by fingerprinting with the moderately repetitive sequence Ca3, J. Clin. Microbiol., (submitted).
Selik, R.M., Starcher, E.T., and Curran, J.W., 1987, Opportunistic diseases reported in AIDS patients: frequencies, associations, and trends, AIDS, 1:175.
Soll, D.R., 1990. Current status of the molecular basis of Candida pathogenicity, in “The Fungal Spore and Disease Inititiation in Plants and Animals”, G.T. Cole and H.G. Hoch, eds., Plenum Publishing Corp., New York (in press).
Soll, D.R., Langtimm, C.A., McDowell, J., Hicks, J., and Galask, R., 1987, High frequency switching in Candida strains isolated from vaginitis patients, J. Clin. Microbiol., 25:1611.
Soll, D.R., Staebell, M., Langtimm, C., Pfaller, M., Hicks, J., and Rao, T.V.G., 1988, Multiple Candida strains in the course of a single systemic infection, J. Clin. Microbiol., 26:1448.
Soll, D.R., Galask, R., Isley, S., Rao, T.V.G., Stone, D., Hicks, J., Schmid, J., Mac, K., and Hanna, C., 1989, “Switching” of Candida albicans during successive episodes of recurrent vaginitis, J. Clin. Microbiol., 27: 681.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Plenum Press, New York
About this chapter
Cite this chapter
Odds, F.C., Schmid, J., Soll, D.R. (1990). Epidemiology of Candida Infections in Aids. In: Bossche, H.V., Mackenzie, D.W.R., Cauwenbergh, G., Van Cutsem, J., Drouhet, E., Dupont, B. (eds) Mycoses in AIDS Patients. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0655-9_5
Download citation
DOI: https://doi.org/10.1007/978-1-4613-0655-9_5
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-7912-9
Online ISBN: 978-1-4613-0655-9
eBook Packages: Springer Book Archive