Abstract
Classical models of control systems for breathing are traditionally based on concepts of oscillatory networks located in medullary or spinal CNS regions, and principally consider influences from metabolic demands, chemical transduction, and thoracic sensors as control parameters. These models are appropriate for the most basic notions of what duties the respiratory control system is supposed to perform, i.e., provide oxygenation and get rid of wastes, but they fail to appreciate a vast array of functions that the respiratory system serves in real life, as opposed to conditions imposed on an anesthetized, paralyzed, temperature-controlled or perhaps decerebrate preparation mounted in a stereotaxic frame or similar restraining device. Moreover, these models provide little assistance in determining the mechanisms causing the dramatic changes in respiratory patterning accompanying different sleep and waking states, changes that are out of all proportion to alterations in metabolic demands during different states.
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© 1989 Plenum Press, New York
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Harper, R.M. (1989). Forebrain Mechanisms Related to Respiratory Patterning During Sleep-Waking States. In: Khoo, M.C.K. (eds) Modeling and Parameter Estimation in Respiratory Control. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0621-4_15
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DOI: https://doi.org/10.1007/978-1-4613-0621-4_15
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-7896-2
Online ISBN: 978-1-4613-0621-4
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