Biochemical and Structural Changes in Uterine Endometrial Cell Types Following Natural or Artificial Deciduogenic Stimuli

- A Review -
  • Stanley R. Glasser
Part of the Trophoblast Research book series (TR, volume 4)


Attachment of the mammalian embryo to the maternal uterus is a signal event in the highly regulated program of synchronized, apparently independent but interdependent events which define unique interactions between two organisms of different genetic derivation. The focus of this essay will be the role of the individual endometrial cell types, vis-a-vis the blastocyst, in these implantation related events. This paper will suggest that at the present time, only a very generalized understanding of the regulatory mechanisms underlying blastocyst attachment has been established. Present models are, therefore, of limited predictive use in resolving problems in human infertility. In an effort to recognize elements with which to formulate a more functional model particular emphasis will be placed on the responses to endocrine, paracrine, and autocrine mechanisms which come into play following the attachment of trophoblast to the uterine epithelium, i.e., the adhesive and post-implantation phases of implantation.


Stromal Cell Trophoblast Cell Endometrial Cell Decidual Cell Trophoblast Invasion 
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Copyright information

© University of Rochester 1990

Authors and Affiliations

  • Stanley R. Glasser
    • 1
  1. 1.Department of Cell BiologyBaylor College of MedicineHoustonUSA

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