Summary
Chiral recognition of several aromatics by cyclodextrins has been studied by fluorescence and circular dichroism spectroscopy. Pyrene forms a chiral excimer in the gamma-cyclodextrin cavity where the primary hydroxyl group side seems to be the recognition site. (S)-Helixed bilirubin is bound preferentially to beta- and gamma-cyclodextrins through hydrogen bonding. No essentially important role of the cyclodextrin cavities is found for the enantioselective complexation between cyclodextrins and bilirubin. Noncyclic oligosaccharides also show their abilities to recognize the chirality of bilirubin. Permethylated beta-cyclodextrin is the most effective host molecule to recognize the chiralities of the binaphthyl derivatives.
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© 1990 Plenum Press, New York
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Kano, K. (1990). Fluorescence and Circular Dichroism Studies on Molecular and Chiral Recognition by Cyclodextrins. In: Atwood, J.L. (eds) Inclusion Phenomena and Molecular Recognition. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0603-0_25
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DOI: https://doi.org/10.1007/978-1-4613-0603-0_25
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