Abstract
The primary sensory neurons enclosed in the dorsal root ganglion (DRG) offer neurobiologists the possibility to test the influence exerted by environmental conditions on the phenotypes expressed by DRG cells. Although the population of the primary sensory neurons originates from a common source, the neural crest, DRG cells differentiate into various neuronal subpopulations which may be distinguished by their peripheral and central projections, electrophysiological properties, enzymatic equipment, pharmacological receptors, neurotransmitter content, cell surface antigens as well as cytochemical and ultrastructural characteristics. The proportion of these neuronal subpopulations shows great fluctuations with the age (Droz and Kazimierczak, 1987), position of the DRG along the neuraxis (Masurich et al., 1986a), or alteration of the innervated targets (Carr and Simpson, 1978; Philippe et al., 1988). It is therefore important to specify the cellular mechanisms which are involved in the remodeling of the neuronal population in DRG.
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© 1990 Plenum Press, New York
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Droz, B., Barakat, I., Kazimierczak, J., Philippe, E., Rochat, A. (1990). Remodeling of Neuronal Subpopulations in Dorsal Root Ganglion: Role of Chemical Factors and Intercellular Contacts. In: Zenker, W., Neuhuber, W.L. (eds) The Primary Afferent Neuron. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0579-8_11
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DOI: https://doi.org/10.1007/978-1-4613-0579-8_11
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