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Calcium Channels

Role in Myometrial Contractility and Pharmacological Applications of Calcium Entry Blockers

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Uterine Function

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Abstract

Calcium plays a major role in a wide range of cellular functions. In the extracellular fluid matrix, calcium is present in millimolar concentrations, whereas free intracellular calcium is up to 10,000 times less plentiful. This compartmentalization is accomplished by (1) limited permeability of the resting plasma membrane to calcium, (2) cellular mechanisms for calcium extrusion, (3) buffering within the cytosol, and (4) sequestration of calcium into intracellular organelles.1

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  1. Division of Perinatal Biology, Departments of Physiology and Pediatrics, School Medicine, Loma Linda University, Loma Linda, California, USA, 92350

    Charles A. Ducsay

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  1. School of Medicine, University of California, Los Angeles, Los Angeles, California, USA

    Mary E. Carsten  & Jordan D. Miller  & 

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© 1990 Plenum Press, New York

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Ducsay, C.A. (1990). Calcium Channels. In: Carsten, M.E., Miller, J.D. (eds) Uterine Function. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0575-0_6

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  • DOI: https://doi.org/10.1007/978-1-4613-0575-0_6

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