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Uterine Function pp 471–500Cite as

Fetal Tissues and Autacoid Biosynthesis in Relation to the Initiation of Parturition and Implantation

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Abstract

The concept that the fetus may regulate the initiation or course of parturition was first expounded over 100 years ago by Speigelberg (cited by Thornburn1). The communication between the fetus and the maternal compartment, particularly in humans, may well be mediated via the amniotic fluid to the amnion tissue. Amnion, in turn, may transduce a signal or signals via the chorion laeve and decidua vera tissues to the myometrium, which ultimately results in the rhythmic contraction of this tissue as well as softening of the cervix. As will be discussed, amnion tissue is ideally suited to be the recipient of such a signal from the fetus via the amniotic fluid. In addition, the amplification of such information may also be a function of this tissue.

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Authors and Affiliations

  1. Departments of Biochemistry and Obstetrics-Gynecology and The Cecil H. and Ida Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, 75235, USA

    Marlane J. Angle & John M. Johnston

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  1. Marlane J. Angle
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  1. School of Medicine, University of California, Los Angeles, Los Angeles, California, USA

    Mary E. Carsten  & Jordan D. Miller  & 

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Angle, M.J., Johnston, J.M. (1990). Fetal Tissues and Autacoid Biosynthesis in Relation to the Initiation of Parturition and Implantation. In: Carsten, M.E., Miller, J.D. (eds) Uterine Function. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0575-0_16

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  • DOI: https://doi.org/10.1007/978-1-4613-0575-0_16

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