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Molecular Mechanisms of Steroid Hormone Action in the Uterus

  • Chapter
Uterine Function

Abstract

As in other organs of the female reproductive tract, the growth and function of uterine tissues are controlled by endocrine factors, primarily the steroid sex hormones secreted by the ovary (and, during pregnancy, the placenta). The initial development of the uterus during puberty and its maintenance in a mature state are principally dependent on the estrogenic hormone estradiol, produced by the ripening ovarian follicle during the follicular phase of the menstrual or estrous cycle. The further proliferation of the uterine endometrium in preparation for the implantation of a fertilized ovum is brought about during the luteal phase by the action of progesterone, originating in the corpus luteum derived from the ruptured follicle after ovulation.

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Jensen, E.V. (1990). Molecular Mechanisms of Steroid Hormone Action in the Uterus. In: Carsten, M.E., Miller, J.D. (eds) Uterine Function. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0575-0_10

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