Abstract
In addition to its well known actions on classic target organs, it has become apparent in recent years that parathyroid hormone (PTH) exerts effects in many other tissues. Thus, PTH has also well-defined effects on lipid metabolism. The hormone stimulates adipose tissue lipolysis in vitro in the experimental animal (1) as well as in the man (2–4). The administration of parathyroid extract into dogs and into human beings induces an increase in serum free fatty acids (3,5).
Keywords
- Parathyroid Hormone
- Primary Hyperparathyroidism
- Human Adipose Tissue
- Uremic Patient
- Serum Free Fatty Acid
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Werner, S.; Löw, H. Stimulation of lipolysis and calcium accumulation by parathyroid hormone in rat adipose tissue after adrenalectomy and administration of high doses of cortisone acetate. Horm. Metab. Res. 5: 292 – 296 (1973)
Gozariu, L.; Forster, K.; Faulhaber, J.D. et al. Parathyroid hormone and calcitonin: Influences on lipolysis of human adipose tissue. Horm. Metab. Res. 6: 243 – 245 (1974)
Sinha, T.K.; Thajchayapon, G.P.; Queener, S.F. et al. On the lipolytic action of parathyroid hormone in man. Metabolism 25: 251 – 260 (1976)
Ziegler, R.; Jobst, W.; Minne, H. et al. Calciotropic hormones and lipolysis of human adipose tissue: Role of extracellular calcium as conditioning but not regulating factor. Endokrinologie 75: 577–588 (1980)
Hallberg, D.; Werner, S. Circulatory and lipolytic effects of parathyroid hormone.Horm. Metab. Res. 9: 424–428 (1977)
De Moor, P.; Creyttens, G.; Bouillon, R. et al. Results obtained in 75 patients operated upon for hyperparathyroidism. Ann. Endocrinol. (Paris) 34: 616–620 (1973)
Christensson, T.; Einarsson, K. Serum lipids before and after parathyroidectomy in patients with primary hyperparathyroidism. Clin. Chim. Acta 78: 411–415 (1977)
Ljunghall, S.; Lithell, H.; Vessby, B. et al. Glucose and lipoprotein metabolism in primary hyperparathyroidism. Effects of parathyroidectomy. Acta Endocrinol (Copenh) 89: 508 –589 (1978)
Vaziri, N.D.; Wellikson, L.; Gwinup, G. et al. Lipid fractions in primary hyperparathyroidism before and after surgical cure. Acta Endocrinol (Copenh) 102: 539–542 (1983)
Paloyan, E.; Kolar, J.; Castles, J. et al. The role of parathyroid hormone in lipid metabolism. Fed. Proc. 22: 676 (1963)
Heuck, C.C.; Ritz, E. Does parathyroid hormone play a role in lipid metabolism? Contrib. Nephrol. 20: 118–128 (1980)
Lazarus, J.M.; Lowrie, E.G.; Hampers, C.L. et al. Cardiovascular disease in uremic patients on hemodialysis. Kidney Int. (suppl.) 7: 167–175 (1975)
Schaefer, K.; Offermann, G.; von Herrath, D. et al. Failure to show a correlation between serum parathyroid hormone, nerve conduction velocity and serum lipids in hemodialysis patients. Clin. Nephrol. 14: 81–88 (1980)
Brunzell, J.D.; Goldberg, A.P. Hormonal regulation of human adipose tissue lipoprotein lipase, in: Schettler, G. et al., editors: Atherosclerosis IV. Berlin, Springer pubi, 1977, p. 336
Cantin, M. Kidney, parathyroid, and lipemia. Lab. Invest. 14: 1691–1698 (1965)
Alfrey, A.C.; Tomford, R.C; Karlinsky, M.L. Effect of parathyroidectomy on nephrotic serum nephritis (abstract). Kidney Int. 18: 530 (1980)
Ritz, E.; Heuck, CC; Boland, R. Phosphate, calcium, and lipid metabolism. Adv. Exp. Med. Biol. 128: 197–208 (1980)
Lacour, B.; Basile, C; Drüeke, T.; Funck-Brentano, J.-L. Parathyroid function and lipid metabolism in the rat. Miner. Electrolyte Metab. 7: 157–165 (1982)
Lacour, B.; Roullet, J.B.; Liagre, A.M. et al. Serum lipoprotein disturbances in primary and secondary hyperparathyroidism and effects of para-thyroidectomy. Am. J. Kidney Dis. 8: 422–429 (1986)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Plenum Press, New York
About this chapter
Cite this chapter
Drüeke, T., Roullet, JB., Lacour, B. (1989). Parathyroid Hormone and Lipid Metabolism. In: Massry, S.G., Fujita, T. (eds) New Actions of Parathyroid Hormone. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0567-5_25
Download citation
DOI: https://doi.org/10.1007/978-1-4613-0567-5_25
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-7870-2
Online ISBN: 978-1-4613-0567-5
eBook Packages: Springer Book Archive