Abstract
The activity and viability of the animal cells strongly depend on the state of the cell membrane. One of the main functions of the latter is known to maintain non-equilibrium distribution of various inorganic ions, specifically, potassium, sodium and calcium concentration gradients. Such state of the cells is reached due to operation of several types of the membrane-located ion-transporting systems including passive ion channels and active ion pumps. At present, because of unique bioelectrochemical properties of cell membrane it’s role as the primary acceptor of microwave radiation is widely discussed1–3. As a result of microwave radiation the changes in passive sodium and potassium fluxes across the erythrocyte’s membrane were reported4–6. In most cases these changes were connected the integral heating of the samples by the microwaves. However, in several reports the evidences have been presented indicating that the active transport through Na/K-ATPase significantly affected by 2450-MHz microwave radiation but only in the narrow region near the point of inflection on an Arrhenius plot6-9 Some specific! interactions between the selected membrane components and microwave radiation have been suggested7,9.
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References
W. R. Adey, Tissue interactions nonionizing electromagnetic fields, Physiol. Rev., 66: 435 (1981).
W. R. Adey, The sequence and energetics of cell membrane transductive coupling to intracellular enzyme systems, Bioelectrochem. Bioenerg., 15: 447 (1986).
N. J. Roberts, jr., S. M. Hichaelson and S. T. Lu, The boilogical effects of radiofrequency radiations a critical review and recomendations, Int. J. Radiat. Biol., 50: 379 (1986).
E. S. Ismailov, Mechanism of the effect of microwaves on the permeabilities of RBS’s for K and Na, Biol, nauki, 3:58 (1971) (In Russian).
R. B. 01cerst,S. Belman,M. Eisenbud,W. W. Mumford and Rabinowitz, The increased passive efflux of sodium and rubidium from rabbit erythrocytes by microwave radiation, Radiat. Res., 82: 244 (1980).
P. D. Fisher, H.J. Poznansky and W. A. G Voss, Effect of mocrowave radiation (2450 MHz) on the active and passive components of Na efflux from human erythrocytes, Radiat. Res., 92: 411 (1982).
J. W. Allis and B. L. Sinha-Robinson, Temperature-specific inhibition of human red cell Na /K ATPase by 2450-MHz microwave radiation, Bioelecmagnetics, 8: 203 (1987).
R. P. Liburdy and A. Penn, Microwave bioeffects in the erythrocytes are temperature and pO dependent: Cation permeability and protein shedding occur at the membrane phase transition, Bioelectromagnetics, 5: 283 (1987).
R.P. Liburdy and P.F. Vanek, jr. Microwaves and the cell membrane, iii. Protein shedding is oxygen and temperature dependent: evidence for cation bridge involvement, Radiat. Res., 109: 382 (1987).
H. Passow, Passive ion permeability of the erythrocyte membrane, Progr. Biophys. and Molec. Biol., 19, part 2: 425 (1969).
P. A. Knauf, G. F. Fuhrmann, S. Rothstein and A. Rothstein, The relationship between anion exchange and net anion flow across the human red blood cell membrane, J. Gen. Physiol., 69: 363 (1977).
G. S. Jones and P. A. Knauf, Mechanism of the increase in cation permeability of human erythrocytes in low-chloride media, J. Gen. Physiol., 86: 721 (1985).
B. Vestergaard-Bogind and Bennekou P., Calcium-induced oscillations in K conductance and membrane potential of human erythrocytes mediatede by the ionophore A23187, Biochem. Biophys. Acta, 688: 37 (1982).
J. H. Sadykov, E. L. Holmuhamedov and Evtodienko Y. V., Effects of pH and proton buffer on oscillations of ion fluxes in rat erythrocytes, Eur. J. Biochem., 113: 369 (1984).
O. Scharff, B. Foder and U. Skibsted, Hysteretic activation of the Ca2+ pump revealed by calcium transients in human red cells, Biochem. Biophys. Acta, 730: 295 (1983).
S. M. Bowin and W. R. Adey, Sensitivity of calcium binding in cerebral tissue to weak enviromental electric fields oscillating at low frequency. Proc. Natl. Acad. Sci. USA, 73: 1999 (1976).
S. K. Dutta, A. Subramoniam and R. Parshad, Microwave-radiation induced calcium efflux from human neyroblastoma cells in culture, Bioelectromagnetics, 5: 71 (1984).
C. F. Blackman, S. G. Benane, D. E. House and W. T. Joines, Effects of ELF (l-120Hz) and modulated (50 Hz) RF fields on the efflux of calcium ions from brain tissue in vitro, Bioelectromagnetics, 6: 1 (1985).
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© 1989 Plenum Press, New York
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Kim, Y.A., Kim, Y.V., Fomenko, B.S., Holmuhamedov, E.L., Akoev, I.G. (1989). Effects Of Microwave Radiation on Inducable Ion Transport of Rat Erythrocytes. In: Allen, M.J., Cleary, S.F., Hawkridge, F.M. (eds) Charge and Field Effects in Biosystems—2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0557-6_21
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DOI: https://doi.org/10.1007/978-1-4613-0557-6_21
Publisher Name: Springer, Boston, MA
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