Skip to main content

Crystallization of Proteins and Other Biological Molecules

  • Chapter
Book cover Crystal Growth in Science and Technology

Part of the book series: NATO ASI Series ((NSSB,volume 210))

Abstract

Major advances in the technology involved in determining protein crystal structures have facilitated several new and existing applications for protein crystallography. Protein crystal growth, the one major bottleneck in this field, has recently received much attention and several new developments hold promise for the future.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. J. C. Kendrew, R. E. Dickerson, B. E. Strandberg, R. G. Hart, D. R. Davies, D. C. Phillips and V. C. Shore, Nature, 185:442 (1960).

    Article  Google Scholar 

  2. J. Goodford, J. Med. Chem., 27:555 (1984).

    Article  Google Scholar 

  3. T. Blundel1, B. L. Sibanda and L. Pearl, Nature, 304:273 (1983).

    Article  Google Scholar 

  4. R. A. Johanson and J. Henkin, J. Biol. Chem., 260:1465 (1985).

    Google Scholar 

  5. T. Wilson and A. Klausner, Biotechnology, 511 (1984).

    Google Scholar 

  6. W. Goddard, Science, 227:917 (1985).

    Article  CAS  Google Scholar 

  7. K. P. Nambiar, J. Stackhouse, D. M. Stauffer, W. D. Kennedy, J. K. Eldredge and S. A. Benner, Science, 223:1299 (1984).

    Article  CAS  Google Scholar 

  8. E. T. Kaiser and D. S. Lawrence, Science, 226:505 (1984).

    Article  CAS  Google Scholar 

  9. L. J. Perry and R. Wetzel, Science, 226:555 (1984).

    Article  CAS  Google Scholar 

  10. A. R. Fersht, J.-P. Shi, J. Knill-Jones, D. M. Lowe, A. J. Wilkinson, D. M. Blow, P. Brick, P. Carter, M. M. Y. Waye and G. Winter, Nature, 314:235 (1985).

    Article  CAS  Google Scholar 

  11. C. S. Craik, C. Largman, T. Fletcher, S. Roczniak, P. J. Barr, R. Fletterick and W. J. Rutter, Science, 228:291 (1985).

    Article  CAS  Google Scholar 

  12. J. Galloway, Nature, 314:228 (1985).

    Article  Google Scholar 

  13. R. P. Wharton and M. Ptashne, Nature, 316:601 (1985).

    Article  CAS  Google Scholar 

  14. D. A. Estell, T. P. Graycar and J. A. Wells, J. Biol. Chem., 260:6518 (1985).

    CAS  Google Scholar 

  15. T. H. Maugh, Science, 223:269 (1984).

    Article  Google Scholar 

  16. T. N. C. Wells and A. R. Fersht, Nature, 316:656 (1985).

    Article  CAS  Google Scholar 

  17. E. Westhof, D. Altschuh, D. Moras, A. C. Bloomer, A. Mondragon, A. Klug and M. H. V. Van Regenmortal, Nature, 311:123 (1984).

    Article  CAS  Google Scholar 

  18. R. J. P. Williams and G. R. Moore, Trends Biochem. Sci., 10:96 (1985).

    Article  Google Scholar 

  19. J. L. Marx, Science, 226:819 (1984).

    Article  CAS  Google Scholar 

  20. J. A. Berzofsky, Science, 229:932 (1985).

    Article  CAS  Google Scholar 

  21. T. L. Blundell and L. M. Johnson, “Protein Crystallography”, Academic Press, New York (1976).

    Google Scholar 

  22. A. A. Kossiakoff, Ann. Rev. Biochem., 54:1195 (1985).

    Article  CAS  Google Scholar 

  23. T. J. Greenhough and J. R. Helliwell, Progr. Biophys. Mol. Biol., 41:67 (1983).

    Article  CAS  Google Scholar 

  24. H. D. Bartunik, P. N. Clout and B. Robrahn, J. Appl. Cryst., 14:134 (1981).

    Article  Google Scholar 

  25. R. Usha, J. E. Johnson, D. Moras, J. C. Thierry, R. Fourme and R. Kahn, J. Appl. Cryst., 17:147 (1984).

    Article  CAS  Google Scholar 

  26. K. S. Wilson, E. A. Stura, D. L. Wild, R. J. Todd, D. J. Stuart, Y. S. Babu, J. A. Jenkins, T. S. Standing, L. N. Johnson, R. Fourme, R. Kahn, A. Gadget, K. S. Bartels and H. D. Bartunik, J. Appl. Cryst., 16:28 (1983).

    Article  CAS  Google Scholar 

  27. U. W. Arndt, T. J. Greenhough, J. R. Helliwell, J. A. K. Howards, S. A. Rule and A. W. Thompson, Nature, 298:835 (1982).

    Article  CAS  Google Scholar 

  28. K. Moffat, D. Szebenyi and D. Bilderback, Science, 223:1423 (1984).

    Article  CAS  Google Scholar 

  29. R. Hamlin, C. Cork, A. Howard, C. Nielson, W. Vernon, D. Matthews, N. G. H. Xuong and V. Perez-Mendiz, J. Appl. Cryst., 14:85 (1981).

    Article  CAS  Google Scholar 

  30. S. C. Harrison, Nature, 309:408 (1984).

    Article  Google Scholar 

  31. W. A. Hendrickson and M. Teeter, Nature, 290:107 (1981).

    Article  CAS  Google Scholar 

  32. W. E. Furey, A. H. Robbins, L. L. Clancy, D. R. Winge, B. C. Wang and C. D. Stout, Science, 231:704 (1986).

    Article  CAS  Google Scholar 

  33. J. L. Smith, W. A. Hendrickson and A. W. Addison, Nature, 303:86 (1983).

    Article  CAS  Google Scholar 

  34. H. Hauptman, S. Potter, C. Weeks, J. Karle, R. Srinivasan, S. Parthasarathy and G. N. Watson, Acta Cryst., A38:289 (1982).

    CAS  Google Scholar 

  35. H. Hauptman, S. Potter and C. M. Weeks, Acta Cryst., A38:294 (1982).

    CAS  Google Scholar 

  36. M. M. Woolfson, Acta Cryst., A40:32 (1984).

    CAS  Google Scholar 

  37. J. Karle, Acta Cryst., A40:l (1984).

    Google Scholar 

  38. J. Karle, Acta Cryst., A40:4 (1984).

    CAS  Google Scholar 

  39. J. Karle, Acta Cryst., A40:526 (1984).

    CAS  Google Scholar 

  40. G. Bricogne, Acta Cryst., A40:410 (1984).

    CAS  Google Scholar 

  41. A. Jones, J. Appl. Cryst., 11:268 (1978).

    Article  CAS  Google Scholar 

  42. A. J. Morffew and D. S. Moss, Acta Cryst., A39:196 (1983).

    CAS  Google Scholar 

  43. P. A. Bash, N. Pattabiraman, C. Huang, T. E. Ferrin and R. Langridge, Science, 222:1325 (1983).

    Article  CAS  Google Scholar 

  44. J. H. Konnert and W. A. Hendrickson, Acta Cryst., A36:344 (1980).

    CAS  Google Scholar 

  45. J. L. Sussman and A. D. Podjarny, Acta Cryst., B39:495 (1983).

    CAS  Google Scholar 

  46. A. G. W. Leslie, Acta Cryst., A40:451 (1984).

    Article  Google Scholar 

  47. O. Herzberg and J. L. Sussman, J. Appl. Cryst., 16:144 (1983).

    Article  CAS  Google Scholar 

  48. A. M. Silva and M. G. Rossmann, Acta Cryst., in press.

    Google Scholar 

  49. A. McPherson, “Preparation and Analysis of Protein Crystals”, John Wiley & Sons, New York (1982).

    Google Scholar 

  50. R. Giege, A. C. Dock, D. Kern, B. Lorber, J. C. Thierry and D. Moras, J. Crystal Growth, 76:554–561 (1986).

    Article  CAS  Google Scholar 

  51. M. Zeppenzauer, H Eklund and E. Zeppenzauer, Arch. Biochem. Biophys., 126:564 (1968)

    Google Scholar 

  52. F. R. Salemme, Arch. Biochem. Biophys., 151:533 (1972).

    Article  CAS  Google Scholar 

  53. Methods in Enzymology, 114:140 (1985).

    Google Scholar 

  54. H. Michel and D. Oesterhelt, Proc. Natl. Acad. Sic., USA., 77:1283 (1980).

    Article  CAS  Google Scholar 

  55. R. M. Garavito and J. P. Rosenbusch, J. Cell Biol., 86:327 (1980).

    Article  CAS  Google Scholar 

  56. J. Deisenhofer, O. Epp, L. Miki, R. Huber and H. Michel, J. Mol. Biol., 180:385 (1984).

    Article  CAS  Google Scholar 

  57. J. Deisenhofer, O. Epp, K. Miki, R. Huber and H. Michel, Nature, 318:618 (1985).

    Article  Google Scholar 

  58. H. Michel, J. Mol. Biol., 158:567 (1982).

    Article  CAS  Google Scholar 

  59. H. Michel, Trends Biochem. Sci., 8:56 (1983).

    Article  CAS  Google Scholar 

  60. H. Michel, EMBO J., 1:1267 (1982).

    CAS  Google Scholar 

  61. R. M. Garavito, J. A. Jenkins, J. N. Jansonius, R. Karlsson and J. P. Rosenbusch, J. Mol. Biol., 164:313 (1983).

    Article  CAS  Google Scholar 

  62. R. M. Garavito, U. Hinz and J. M. Neuhaus, J. Biol. Chem., 259:4254 (1984).

    CAS  Google Scholar 

  63. J. P. Allen and G. Feher, Proc. Natl. Acad. Sci., USA., 81:4795 (1984).

    Article  CAS  Google Scholar 

  64. W. Welte, T. Wacher, M. Leis, W. Kreutz, J. Shinozawa, N. Gad’on and G. Drews, FEBS Letters, 182:260 (1985).

    Article  CAS  Google Scholar 

  65. C.-H. Chang, M. Schiffer, D. Tiede, U. Smith and J. Norris, J. Mol. Biol., 186:201 (1985).

    Article  CAS  Google Scholar 

  66. A. McPherson, S. Koszelak, H. Axelrod, J. Day, R. Williams, L. Robinson, M. McGrath and D. Cascid, J. Biol. Chem., 261:1969–1975 (1986).

    CAS  Google Scholar 

  67. J. Schlichtkrul1, Acta Chem. Scand., 11:439 (1957).

    Article  Google Scholar 

  68. R. W. Fiddis, R. A. Longman and P. D. Calvert, Trans. Faraday Soc., 75:2753 (1979).

    Article  CAS  Google Scholar 

  69. Z. Kam, H. B. Shore and G. Feher, J. Mol. Biol., 123:539 (1978).

    Article  CAS  Google Scholar 

  70. M. L. Pusey, R. S. Snyder and R. Naumann, J. Biol. Chem., 261:6524–6529 (1986).

    CAS  Google Scholar 

  71. G. Feher and Z. Kam, Methods in Enzymology, 114:78–110 (1985).

    Article  Google Scholar 

  72. F. Rosenberger, J. Crystal Growth, 76:618–638 (1986).

    Article  CAS  Google Scholar 

  73. R. J. Davey, J. Crystal Growth, 76:637–644 (1986).

    Article  CAS  Google Scholar 

  74. W. A. Tiller, J. Crystal Growth, 76:607–617 (1986).

    Article  CAS  Google Scholar 

  75. M. Pusey and R. Naumann, J. Crystal Growth, 76:593–599 (1986).

    Article  CAS  Google Scholar 

  76. S. D. Durbin and G. Feher, J. Crystal Growth, 76:583–592 (1986).

    Article  CAS  Google Scholar 

  77. Dan Carter, NASA Protein Crystal Growth Meeting, December (1986).

    Google Scholar 

  78. F. L. Suddath, L. J. Wilson and J. Bertrand, Dynamic Control of Protein Crystallization, American Crystallographic Association Meeting, March 15-20, Austin, Texas, Abst. H-2 (1987).

    Google Scholar 

  79. N. D. Jones, J. B. Decter, J. K. Swartzendernber and P. L. Landis, Apocalypse-An Automated Protein Crystallization System, American Crystallographic Association Meeting, March 15-20, Austin, Texas, Abst. H-4 (1987).

    Google Scholar 

  80. K. B. Ward, M. A. Perozzo and W. M. Zuk, Automated Preparation of Protein Crystals Using Laboratory Robotics and Automated Visual Inspection, American Crystallographic Association Meeting, March 15-20, Austin, Texas, Abst. H-3 (1987).

    Google Scholar 

  81. P. C. Weber and M. J. Cox, Experiments in Automated Protein Crystal Growth, American Crystallographic Association Meeting, March 15-20, Austin, Texas, Abst. H-5 (1987).

    Google Scholar 

  82. K. B. Ward, M. A. Perozzo and J. R. Deschamps, Automation of protein crystallization experiments, in: “Automation of Protein Crystallization Experiments”

    Google Scholar 

  83. J. R. Strimaitis and G. L. Hawk, eds., pp 413–433, Zymark Corporation, Hopkinton, Massachusetts.

    Google Scholar 

  84. N. D. Jones and K. B. Ward, A New Protein Crystallization Plate, Abstract of American Crystallographic Association Annual Meeting, June 22-27, PA-26 (1986).

    Google Scholar 

  85. W. M. Zuk and K. B. Ward, Robotics in the Industrial Laboratory, Preparation of Protein Crystals Using Robotics and Automated Visual Inspection, 93rd ACS National Meeting, Denver, Section B, paper 49.

    Google Scholar 

  86. W. M. Zuk and K. B. Ward, Detection and Monitoring of Crystal Growth in Protein Crystallography Experiments Using Automated Image Analysis, American Crystallographic Association Meeting, Austin, Texas.

    Google Scholar 

  87. C. W. Carter, Jr. and C. W. Carter, J. Biol. Chem., 254:12219–12223 (1979).

    Google Scholar 

  88. E. T. Baldwin, K. V. Crumley and C. W. Carter, Jr., Biophys. J., 49:47–48 (1986).

    Article  CAS  Google Scholar 

  89. G. E. Rindome, ed., “Materials Processing in the Reduced Gravity Environment of Space”, North-Holland, New York (1982).

    Google Scholar 

  90. W. Littke and C. John, Science, 225:203 (1984).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1989 Plenum Press, New York

About this chapter

Cite this chapter

Bugg, C.E. (1989). Crystallization of Proteins and Other Biological Molecules. In: Arend, H., Hulliger, J. (eds) Crystal Growth in Science and Technology. NATO ASI Series, vol 210. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0549-1_16

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-0549-1_16

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-7861-0

  • Online ISBN: 978-1-4613-0549-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics