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Transport of Lipids and Proteins During Membrane Flow in Eukaryotic Cells

  • Chapter
Organelles in Eukaryotic Cells

Abstract

Phospholipid molecules constitute the essential building blocks of biological membranes. They are arranged according to a bilayer structure while membrane proteins are embedded in or attached to this double layer of lipid molecules. Besides phospholipids, eukaryotic cell and organelle membranes may contain two other lipid classes:cholesterol and glycosphingolipids. As may be anticipated, proteins and the various lipid classes are not uniformly distributed among membranes, given the distinct functions of the intracellular organelles. Yet, de novo biosynthesis of both lipids and proteins occurs primarily at the endoplasmic reticulum. This implies that specific mechanisms must exist that determine the fate and distribution of these compounds among membranes. Obviously, this sets particular requirements to intracellular sorting and transport phenomena.

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Authors and Affiliations

  1. Laboratory of Physiological Chemistry, University of Groningen, Bloemsingel, 10 9712 KZ, Groningen, The Netherlands

    Dick Hoekstra, Sinikka Eskelinen & Jan Willem Kok

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  1. Dick Hoekstra
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  2. Sinikka Eskelinen
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  3. Jan Willem Kok
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Editors and Affiliations

  1. University of Amsterdam, Amsterdam, The Netherlands

    Joseph M. Tager

  2. University of Bern, Bern, Switzerland

    Angelo Azzi

  3. University of Bari, Bari, Italy

    Sergio Papa  & Ferruccio Guerrieri  & 

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© 1989 Plenum Press, New York

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Hoekstra, D., Eskelinen, S., Kok, J.W. (1989). Transport of Lipids and Proteins During Membrane Flow in Eukaryotic Cells. In: Tager, J.M., Azzi, A., Papa, S., Guerrieri, F. (eds) Organelles in Eukaryotic Cells. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0545-3_5

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  • DOI: https://doi.org/10.1007/978-1-4613-0545-3_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-7859-7

  • Online ISBN: 978-1-4613-0545-3

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