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Functions, Biogenesis and Pathology of Peroxisomes in Man

  • Chapter
Organelles in Eukaryotic Cells

Abstract

Peroxisomes (microbodies; microperoxisomes), were first described morphologically by Rhodin (1) in 1954 and characterized biochemically by De Duve and coworkers (2) in the early 1960’s. They are defined as intracellular organelles bounded by a single membrane and containing catalase and H202-producing oxidases. This definition emphasizes the oxidative functions of peroxisomes. However, the peroxisome is a highly versatile organelle. While oxidative processes are certainly a characteristic feature of the metabolic pathways in which peroxisomes participate other types of reactions, too, occur in peroxisomes.

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Authors and Affiliations

  1. E.C. Slater Institue for Biochemical Research, University of Amsterdam, Academic Medical Centre, Amsterdam, The Netherlands

    Erik A. C. Wiemer, Stanley Brul, Abraham Bout, Anneke Strijland, Judith C. Heikoop, Rob Benne & Joseph M. Tager

  2. Department of Pediatrics, University of Amsterdam, Academic Medical Centre, Amsterdam, The Netherlands

    Ronald J. A. Wanders

  3. Department of Human Genetics, University of Amsterdam, Academic Medical Centre, Amsterdam, The Netherlands

    Andries Westerveld

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  1. University of Amsterdam, Amsterdam, The Netherlands

    Joseph M. Tager

  2. University of Bern, Bern, Switzerland

    Angelo Azzi

  3. University of Bari, Bari, Italy

    Sergio Papa  & Ferruccio Guerrieri  & 

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© 1989 Plenum Press, New York

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Wiemer, E.A.C. et al. (1989). Functions, Biogenesis and Pathology of Peroxisomes in Man. In: Tager, J.M., Azzi, A., Papa, S., Guerrieri, F. (eds) Organelles in Eukaryotic Cells. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0545-3_3

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  • DOI: https://doi.org/10.1007/978-1-4613-0545-3_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-7859-7

  • Online ISBN: 978-1-4613-0545-3

  • eBook Packages: Springer Book Archive

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