Abstract
The majority of the mitochondrial proteins are encoded by nuclear DNA, synthesized in the cytosol on free cytoplasmic ribosomes and subsequently taken up by mitochondria where they are rendered functional. Most nuclear-coded mitochondrial proteins are synthesized as larger molecular weight precursors, which contain an amino-terminal extension. They are cleaved by a specific matrix protease upon translocation of the precursor into mitochondria (for Ref. see 1).
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© 1989 Plenum Press, New York
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Marra, E., Giannattasio, S., Quagliariello, E. (1989). In Vitro Synthesis and Import of Mitochondrial Proteins. In: Tager, J.M., Azzi, A., Papa, S., Guerrieri, F. (eds) Organelles in Eukaryotic Cells. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0545-3_16
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DOI: https://doi.org/10.1007/978-1-4613-0545-3_16
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