Abstract
The purpose of this ongoing study is to determine whether thoracic radiotherapy for lung cancer produces an early increase in serum copper (Cu) concentration, an increase which might predict clinical outcome. Copper and iron concentrations were measured in serum obtained from nonsmall cell lung cancer patients at 0,1, 2, 4, and 6 weeks after the start of radiotherapy. Control groups included patients irradiated for breast cancer (low dose of radiation to the lung), for endometrial, cervical or prostatic cancer (no dose to lung), and patients with congestive heart failure, pulmonary hypertension, chronic obstructive pulmonary disease (COPD), and cutaneous burns with or without smoke inhalation (no irradiation).
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Molteni, A. et al. (1989). Serum Copper Concentration as an Index of Clinical Lung Injury. In: Kies, C. (eds) Copper Bioavailability and Metabolism. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0537-8_25
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DOI: https://doi.org/10.1007/978-1-4613-0537-8_25
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