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The Effect of Exercise on the Central and Peripheral Chemoreceptor Thresholds to Carbon Dioxide in Man

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Respiratory Control

Abstract

In the development of a model for the control of breathing during exercise, it is necessary to include an exercise drive to ventilation to account for the sudden changes in ventilation which occur at the start and end of exercise. There are two main ways in which such an exercise drive to ventilation may be introduced. First, the exercise drive could be simply added to ventilation, independent of the chemoreceptor mediated drives, an assumption made by a number of modellers. Alternatively, the exercise drive could interact with the chemoreceptor drives, such as by potentiating the effect of the peripheral chemoreceptors, or by lowering the thresholds to carbon dioxide2. The term threshold is used here to designate the carbon dioxide level, above which, ventilation increases linearly with a further rise in carbon dioxide, and below which, ventilation is independent of carbon dioxide.

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© 1989 Plenum Press, New York

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Duffin, J. (1989). The Effect of Exercise on the Central and Peripheral Chemoreceptor Thresholds to Carbon Dioxide in Man. In: Swanson, G.D., Grodins, F.S., Hughson, R.L. (eds) Respiratory Control. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0529-3_7

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  • DOI: https://doi.org/10.1007/978-1-4613-0529-3_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-7851-1

  • Online ISBN: 978-1-4613-0529-3

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