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Respiratory Control pp 43–52Cite as

The Validity of the Cardiodynamic Hypothesis for Exercise Hyperpnea in Man

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Abstract

According to the cardiodynamic hypothesis proposed by Wasserman et al.,1,2 CO2 flow from venous blood to the lung (QCO2), i.e., the product of cardiac output (Q) and mixed venous CO2 content (CVCO2), causes an increase in ventilation during exercise by means of some unidentified mechanisms. Close correlation between CO2 output (VCO2) and ventilation (VE) has repeatedly been observed during the steady- and unsteady-state of exercise.3,4,5 More recently, Miyamoto et al.6 have determined the kinetics of Q by adopting an ensemble-averaging technique to impedance cardiography, evidently showing that the change in Q precedes that in VE during the unsteady- state, of step, impulse and sinusoidal exercise.5 However, the mechanism which links CO2 flow to hyperpnea remains uncertain.

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References

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Author information

Authors and Affiliations

  1. Department of Information Engineering, Faculty of Engineering, Yamagata University, Yonezawa 992, Japan

    Y. Miyamoto, T. Sugawara, Y. Nakazono, K. Kawahara & M. Mussell

  2. Department of Physiology, Yamagata University School of Medicine, Yamagata, 990-23, Japan

    K. Niizeki

Authors
  1. Y. Miyamoto
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  2. K. Niizeki
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  3. T. Sugawara
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  4. Y. Nakazono
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  5. K. Kawahara
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  6. M. Mussell
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Editor information

Editors and Affiliations

  1. University of Colorado Health Science Center, Denver, Colorado, USA

    George D. Swanson

  2. California State University, Chico, Chico, California, USA

    George D. Swanson

  3. Late of University of Southern California, Los Angeles, California, USA

    Fred S. Grodins

  4. University of Waterloo, Waterloo, Ontario, Canada

    Richard L. Hughson

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© 1989 Plenum Press, New York

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Miyamoto, Y., Niizeki, K., Sugawara, T., Nakazono, Y., Kawahara, K., Mussell, M. (1989). The Validity of the Cardiodynamic Hypothesis for Exercise Hyperpnea in Man. In: Swanson, G.D., Grodins, F.S., Hughson, R.L. (eds) Respiratory Control. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0529-3_5

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  • DOI: https://doi.org/10.1007/978-1-4613-0529-3_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-7851-1

  • Online ISBN: 978-1-4613-0529-3

  • eBook Packages: Springer Book Archive

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