Ventilatory Responses to Short Carotid Sinus Pressure Stimuli: Interpretation Using a Model of Rhythm Generation

  • Roberto Maass-Moreno
  • Peter G. Katona


Understanding how the respiratory system responds to complex stimuli, such as exercise, requires an understanding of the integrative control of the cardiovascular and respiratory systems. This paper deals with one aspect of the control of such systems, namely, the reflex inhibition of ventilation upon stimulating the carotid sinus baroreceptors. Although the existence of a reflex from baroreceptors to ventilation was described by Heymans and Neil (5), this reflex has received relatively little attention until quite recently (3,4). The goal of this paper is to describe the dependence of the ventilatory responses on the timing of brief intracarotid pressure stimuli within a respiratory cycle, and to interpret the results in terms of the model of respiratory rhythm generation proposed by Richter et al.(9) using the mathematical description of Botros (2).


Ventilatory Response Carotid Sinus Neuron Pool Pressure Stimulus Phrenic Nerve Activity 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Roberto Maass-Moreno
    • 1
  • Peter G. Katona
    • 1
  1. 1.Department of Biomedical EngineeringCase Western Reserve UniversityClevelandUSA

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