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Dynamics of the Ventilatory Controller and Hypoxic Stimulation in Man

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Respiratory Control
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Abstract

Since the pioneering work of Grodins et al. 1 with dynamic modelling of the chemical ventilatory control, it has been assumed that the neural network controlling ventilation could be modelled as a linear system with no dynamics of its own2. In dynamic models, the control system is usually divided: (i) a controlled system whith circulation and diffusion of CO2 and O2 in the lungs, blood vessels and tissue compartments, and (ii) an active controlling system consisting of the generation of receptors discharge, integration of the stimuli and generation of ventilatory drive by the brainstem centers, and finally activation of ventilatory muscles by the spinal motoneurons.

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References

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© 1989 Plenum Press, New York

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Bertholon, J.F., Eugene, M., Labeyrie, E., Teillac, A. (1989). Dynamics of the Ventilatory Controller and Hypoxic Stimulation in Man. In: Swanson, G.D., Grodins, F.S., Hughson, R.L. (eds) Respiratory Control. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0529-3_26

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  • DOI: https://doi.org/10.1007/978-1-4613-0529-3_26

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-7851-1

  • Online ISBN: 978-1-4613-0529-3

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