Abstract
It has been postulated that the overall effects of aging may be related to the effectiveness of control mechanisms in maintaining homeostasis1. Age-related losses appear greatest in pursuits requiring the integrated activity of a number of organ systems. The response to exercise exemplifies such an integrated response of control mechanisms, particularly during the dynamic, non-steady state phases of the adjustment to changing energy demands. The present report outlines studies from our laboratory describing age-related changes in the dynamics of oxygen uptake during the on-transient response to exercise. Oxygen kinetics were examined in response to various exercise perturbations including ramp, square wave and sinusoidal forcings on the cycle ergometer. Studies were performed in the elderly compared to the young, and also in a group of 97 subjects spanning the age range from 22 to 84 years.
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References
N. W. Shock, Systems physiology and aging, Fed. Proc., 38:161–162 (1979).
W. L. Beaver, N. Lamarra, and K. Wasserman, Breath-by-breath measurement of true alveolar gas exchange, J. Appl. Physiol., 51:1662–1675 (1981).
B. J. Whipp, J. A. Davis, F. Torres, and K. Wasserman, A test to determine parameters of aerobic function during exercise, J. Appl. Physiol., 50:217–221 (1981).
J. A. Davis, P. Vodak, J. H. Wilmore, J. Vodak, and P. Kurtz, Anaerobic threshold and maximal aerobic power for three modes of exercise, J. Appl. Physiol., 41:544–550 (1976).
N. L. Jones and R. E. Ehrsam, The anaerobic threshold, Exer. Spt. Sci. Rev., 10:49–83 (1982).
J. A. Davis, B. J. Whipp, N. Lamarra, D. J. Huntsman, M. H. Frank, and K. Wasserman, Effect of ramp slope on determination of aerobic parameters from the ramp exercise test, Med. Sci. Sports Exerc., 14:339–343 (1982).
D. Linnarson, Dynamics of pulmonary gas exchange and heart rate changes at the start and end of exercise, Acta Physiol. Scand., Suppl. 415:1–68 (1974).
B. J. Whipp, S. A. Ward, N. Lamarra, J. A. Davis, and K. Wasserman, Parameters of ventilatory and gas exchange dynamics during exercise, J. Appl. Physiol., 52:1506–1513 (1982).
R. Casaburi, B. J. Whipp, K. Wasserman, W. L. Beaver, and S. N. Koyal, Ventilatory and gas exchange kinetics in response to sinusoidal work, J. Appl. Physiol., 42:300–311 (1977).
H. L. Taylor, E. Buskirk, and A. Henschal, Maximal oxygen uptake as an objective measure of cardiorespiratory performance, J. Appl. Physiol., 8:73–80 (1955).
V. L. Foster, G. J. E. Hume, A. L. Dickinson, S. J. Chatfield, and W. C. Byrnes, The reproducibility of VO2max, ventilatory and lactate thresholds in elderly women, Med. Sci. Sports Exerc., 18:425–430 (1986).
R. L. Hughson and M. D. Inman, Oxygen uptake kinetics from ramp work test: Variability of single test values, J. Appl. Physiol., 61:373–376 (1986).
H. A. de Vries, R. A. Wiswell, G. Romero, T. Monitani, and R. Bulbulian, Comparison of oxygen kinetics in young and old subjects, Eur. J. Appl. Physiol., 49:277–286 (1982).
E. R. Buskirk and J. L. Hodgson, Age and aerobic power: the rate of change in men and women, Fed. Proc., 46:1827–1829 (1987).
A. A. Vandervoort and A. J. McComas, Contractile changes in opposing muscles of the human ankle joint with aging, J. Appl. Physiol., 61:361–367 (1986).
J. Lexell, K. Henriksson-Larsen, B. Winblad, and M. Sjostrom, Distribution of different fibre types in human skeletal muscles: Effects of aging studied in whole muscle cross sections, Muscle and Nerve, 6:588–595 (1983).
J. E. Himann, D. A. Cunningham, P. A. Rechnitzer, and D. H. Paterson, Age-related changes in speed of walking, Med. Sci. Sports Exerc., 20:161–166 (1988).
K. R. Brizzee, Neuron aging and neuron pathology, in: “Relations Between Normal Aging and Disease,” H. A. Johnson, ed., Raven Press, New York (1985).
D. R. Seals, J. M. Hagberg, B. F. Hurley, A. A. Ehsani, and J. O. Holloszy, Endurance training in older men and women. I. Cardiovascular responses to exercise, J. Appl. Physiol., 61:361–367 (1986).
D. A. Cunningham, P. A. Rechnitzer, J. H. Howard, and A. P. Donner, Exercise training of men at retirement: A clinical trial, J. Gerontol., 42:17–23 (1987).
D. H. Paterson, D. A. Cunningham, J. E. Himann, and P. A. Rechnitzer, Long-term effects of exercise training on VO2max in older men, Can. J. Spt. Sci., 13:74–75P (1988).
B. J. Whipp and M. Mahler, Dynamics of pulmonary gas exchange, in: “Pulmonary Gas Exchange, Volume II, Organism and Environment”, J. B. West, ed., Academic Press, New York (1980).
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© 1989 Plenum Press, New York
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Paterson, D.H., Cunningham, D.A., Babcock, M.A. (1989). Oxygen Kinetics in the Elderly. In: Swanson, G.D., Grodins, F.S., Hughson, R.L. (eds) Respiratory Control. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0529-3_19
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DOI: https://doi.org/10.1007/978-1-4613-0529-3_19
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