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The Concept of Homology in Comparative Mammalian Teratology

  • James R. Miller

Abstract

Naturally occurring animal models provide a fashionable topic in current mammalian biology. The subject is not a fad; the ancient Egyptians recognized the unity of human and veterinary medicine (Sigerist, 1951), and a considerable degree of interdependence has marked the development of the two disciplines. More recently, extensive reviews (Patterson et al., 1982; Leiter et al., 1987), proceedings of symposia (Lindsey and Capen, 1976; Kawamata and Melby, 1987) and workshops (Hackel, 1980), monographs (Andrews et al., 1979), and numerous research reports devoted to spontaneous animal models have appeared at regular intervals; the entry “Disease models, animal,” which first appeared in Index Medicus in 1970, regularly includes a number of references related to naturally occurring diseases; since 1969 the Institute of Laboratory Animal Resources (ILAR), with the support of the Animal Resources Branch of the National Institutes of Health, has maintained a registry of animal models and genetic stocks (Anonymous, 1972); and some of the techniques of molecular biology are being used to create new models (Evans et al., 1985; Hooper et al., 1987; Kuehn et al., 1987).

Keywords

Growth Plate Cleft Palate Syrian Hamster Homologous Relation Ectodermal Dysplasia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • James R. Miller
    • 1
  1. 1.Central Research DivisionTakeda Chemical IndustriesOsakaJapan

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