Regulation of the Expressed Idiotypic Repertoire in the Normal Immune Response of the Aged
Aging is accompanied by a gradual decline of certain physiological functions. Not the least of these are the effector functions of the immune system. Most aging animals demonstrate a progressive decline in their capacity to mount primary immune responses when compared in magnitude and heterogeneity of antibody affinity with that seen in the immune response of young adult animals.
KeywordsAged Mouse Aged Donor Antibody Affinity Primary Immune Response Fetal Liver Cell
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