Antenatal Sonographic Findings of Agenesis of Corpus Callosum

  • Patrizia Vergani
  • Nicola Strobelt
Part of the Advances in Behavioral Biology book series (ABBI, volume 42)


The corpus callosum consists of predominantly white fibers connecting the cerebral hemispheres. It develops in the upper portion of the lamina terminalis, in the cephalic extremity of the neural tube near the closure point of the rostral neuropore. Among the three telencephalic commissures, the anterior commissure, the fornix and the corpus callosum, the latter is the last structure that undergoes development. The anterior commissure appears in the second month of gestation, the fornix develops in the third month and while the fornix is partially regressing, the first outlines of the corpus callosum can be identified during the fourth month.


Corpus Callosum Lateral Ventricle Anterior Commissure Fetal Head Frontal Horn 
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  1. Atlas, S.W., Zimmerman, R.A., Bilaniuk, L.T., et al., 1986, Corpus callosum and limbic system: Neuroanatomic MR evaluation of developmental anomalies, Radiology 160: 355.PubMedGoogle Scholar
  2. Babcock, D.S., 1984, The normal, absent and abnormal corpus callosum: Sonographic findings, Radiology 151: 449.PubMedGoogle Scholar
  3. Byrd, S.E., Harwood-Nash, D.C., and Fitz, C.R., 1978, Absence of the corpus callosum: Computed tomographic evaluation in infants and children, J. Can. Assoc. Radiol. 29: 108.PubMedGoogle Scholar
  4. Chervenak, F.A., Hobbins, J.C., Wertheimer, I. et al, 1985, The natural history of ventriculomegaly in a fetus without obstructive hydrocephalus, Am. J. Obstet. Gynecol. 152: 574.PubMedGoogle Scholar
  5. Comstock, C.H., Culp, D., Gonzalez, J. et al., 1985, Agenesis of the corpus callosum in the fetus: Its evolution and significance, J. Ultrasound. Med. 4: 613.PubMedGoogle Scholar
  6. Gebarski, S.S., Gebarski, K.S., Bowerman R. et al., 1984, Agenesis of the corpus callosum: Sonographic features, Radiololgy 151: 443.Google Scholar
  7. Parrish, M.L., Roessmann, U., and Levinsohn, M.W., 1979, Agenesis of the corpus callosum: A study of the frequency of associated malformations, Ann. Neurol. 6: 349.PubMedCrossRefGoogle Scholar
  8. Romero, R., Pilu, G., Jeanty, A. et al., 1988, Agenesis of corpus callosum, in: “Prenatal Diagnosis of Congenital Anomalies,” R. Romero et al., eds, Appleton & Lange, East Norwalk, CT.Google Scholar
  9. Vergani, P., Ghidini, A., Mariani, S. et al., 1988, Antenatal sonographic findings of agenesis of corpus callosum, Am. J. Perinatol. 5: 105.PubMedCrossRefGoogle Scholar
  10. Young, I.D., Trounce, J.Q., Levene, M.I. et al., 1985, Agenesis of the corpus callosum and macrocephaly in siblings, Clin. Genet. 28: 225.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1994

Authors and Affiliations

  • Patrizia Vergani
    • 1
  • Nicola Strobelt
    • 1
  1. 1.Dept. of Obstetrics GynecologyOspedale San Gerardo di MonzaMonzaItalia

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