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Other Syndromes Frequently Associated with Callosal Agenesis

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Callosal Agenesis

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 42))

Abstract

More than 50 disorders associated with agenesis of the corpus callosum (ACC) have been reported in medical literature. In most cases, the association appears to be a chance occurrence. Some of the cases have chromosomal abnormalities, others have central nervous malformation or metabolic disease and a few have peroxysomal disease or apparently unrelated systemic malformations (see Tables 1 and 2). A number of cases without concomitant pathology have also been described. Clinicians are at present considering the possibility that inherited metabolic disease may be responsible for cerebral malformations (Dobyns, 1989; Kolodny, 1989). In this context, we recently examined a brother and sister similarly afflicted with a complex neurological syndrome and an unusual metabolic abnormality of lipids. Both had agenesis of the cerebellar vermis.

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  1. Service de Neurologie, Département de Pédiatrie, Hôpital Sainte-Justine pour les Enfants, 3175, Chemin Côte Ste. Catherine, Montréal, Qué., H3T 1C5, Canada

    Guy Geoffroy

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  1. Université de Montréal, Montréal, Québec, Canada

    Maryse Lassonde

  2. University of St. Andrews, St. Andrews, Scotland, UK

    Malcolm A. Jeeves

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© 1994 Plenum Press, New York

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Geoffroy, G. (1994). Other Syndromes Frequently Associated with Callosal Agenesis. In: Lassonde, M., Jeeves, M.A. (eds) Callosal Agenesis. Advances in Behavioral Biology, vol 42. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0487-6_7

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  • DOI: https://doi.org/10.1007/978-1-4613-0487-6_7

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  • Print ISBN: 978-1-4612-7592-3

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