Advertisement

The Development of Interhemispheric Transfer of Tactile Information in Cases of Callosal Agenesis

  • Gina M. Geffen
  • Judith Nilsson
  • Donald A. Simpson
  • Malcolm A. Jeeves
Part of the Advances in Behavioral Biology book series (ABBI, volume 42)

Abstract

Congenital absence of corpus callosum in relatively asymptomatic individuals raises the question of mechanisms responsible for interhemispheric transfer of information. Possible alternative methods of communication between the cerebral hemispheres involve the anterior commissure, subcortical commissural pathways, bilateral representation of functions that are normally predominantly under unilateral control, enhanced transmission of information on the ipsilateral sensory and motor pathways, and behavioral cross-cueing (Jeeves, 1990). Before it is possible to pinpoint a particular mechanism, it is necessary to determine whether subjects with congenital absence of the corpus callosum (ACC) differ from normal individuals when performing tasks that require interhemispheric transfer, and whether transfer deficits, where present, are similar in magnitude to those shown by patients with surgical section (partial or complete) of the corpus callosum. We report a study of seven cases of callosal agenesis using a tactile finger localization task previously shown to be sensitive to extent and location of acquired lesions of the corpus callosum (Geffen et al., 1985). Developmental improvements in interhemispheric transfer in normal children were also elicited using this task (Quinn and Geffen, 1986). However, the proposal that this improvement reflects the concomitant myelination of the corpus callosum between ages 5–11 years has been questioned (Pipe, 1991).

Keywords

Corpus Callosum Anterior Commissure Congenital Absence Tactile Information Interhemispheric Transfer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Annett, M., 1970, A classification of hand preference by association analysis, Br. J. Psychol. 61: 303–321.PubMedCrossRefGoogle Scholar
  2. Chiarello, C., 1980, A house divided? Cognitive functioning with callosal agenesis, Brain Lang. 11: 128–158.PubMedCrossRefGoogle Scholar
  3. Clark, C.R. and Geffen, G.M., 1990, Hemispheric equivalence for simultaneity judgements of somatosensory stimuli, Cog. Neuropsychol. 7: 311–327.CrossRefGoogle Scholar
  4. Dennis, M., 1976, Impaired sensory and motor differentiation with corpus callosum agenesis: A lack of callosal inhibition during ontogeny?, Neuropsychologia 14: 455–469.PubMedCrossRefGoogle Scholar
  5. Ettlinger, G., Blakemore, C.B., Milner, A.D., and Wilson, J., 1972, Agenesis of the corpus callosum: a behavioural investigation, Brain 95: 327–346.PubMedCrossRefGoogle Scholar
  6. Field, M., Ashton, R., and White, K., 1978, Agenesis of the corpus callosum: report on two pre-school children and review of the literature, Dev. Med. Child Neurol. 20: 47–61.PubMedCrossRefGoogle Scholar
  7. Gandevia, S.C., 1978, The sensation of heaviness after surgical disconnection of the cerebral hemispheres in man, Brain 101: 295–305.PubMedCrossRefGoogle Scholar
  8. Gazzaniga, M. S., 1970, “The Bisected Brain,” Appleton-Century-Crofts, New York.Google Scholar
  9. Geffen, G., Nilsson, J., Quinn, K., and Teng, E.L., 1985, The effect of lesions of the corpus callosum on finger localization, Neuropsychologia 23: 497–514.PubMedCrossRefGoogle Scholar
  10. Jeeves, M.A., 1965, Psychological studies of three cases of congenital agenesis of the corpus callosum, in: “Functions of the Corpus Callosum,” E. G. Ettlinger, ed., Churchill Livingstone, London.Google Scholar
  11. Jeeves, M.A., 1979, Some limits to interhemispheric integration in cases of callosal agenesis and partial commissurotomy, in: “Structure and Function of the Cerebral Commissures,” I. S. Russell, M. W. van Hof and G. Berlucchi, eds., University Park Press, Baltimore, Md.Google Scholar
  12. Jeeves, M.A., 1990, Agenesis of the corpus callosum, in: “Handbook of Neuropsychology,” Vol. 4, F. Boller and J. Grafman, eds., Elsevier, North Holland, Amsterdam.Google Scholar
  13. Jeeves, M.A. and Rajalakshmi, R., 1964, Psychological studies of a case of congenital agenesis of the corpus callosum, Neuropsychologia 2: 247–252.CrossRefGoogle Scholar
  14. Laget, P., D’Allest, A.M., Fihey, R., and Lortholary, O., 1977, L’intérêt des potentials évoqués somesthésiques homolatéraux dans les agénésies du corps calleux, Rev. E.E.G. Neurophysiol. Clin. 7: 498–502.Google Scholar
  15. Lassonde, M., Sauerwein, H., McCabe, N., Laurencelle, L., and Geoffroy, G., 1988, Extent and limits of cerebral adjustment to early section of the corpus callosum, Behay. Brain Res. 30: 165–181.CrossRefGoogle Scholar
  16. McCloskey, D.I., 1973, Position sense after surgical disconnexion of the cerebral hemispheres in man, Brain 96: 269–276.PubMedCrossRefGoogle Scholar
  17. Pandya, D. P. and Seltzer, B., 1986, The topography of commissural fibers, in: “Two Hemispheres-One Brain: Functions of the Corpus Callosum,” F. Lepore, M. Ptito, and H. H. Jasper, eds., Alan R. Liss, New York.Google Scholar
  18. Pipe, M., 1991, Developmental changes in finger localization, Neuropsychologia 29: 339–342.PubMedCrossRefGoogle Scholar
  19. Quinn, K. and Geffen, G., 1986, The development of tactile transfer of information, Neuropsychologia 24: 793–804.PubMedCrossRefGoogle Scholar
  20. Reynolds, D. and Jeeves, M.A., 1977, Further studies of tactile perception and motor co-ordination in agenesis of the corpus callosum, Cortex 13: 257–272.PubMedGoogle Scholar
  21. Sauerwein, H.C., Lassonde, M.C., Cardu, B., and Geoffroy, G., 1981, Interhemispheric integration of sensory and motor functions in agenesis of the corpus callosum, Neuropsychologia 19: 445–454.PubMedCrossRefGoogle Scholar
  22. Saul, R.E. and Gott, P.S., 1973, Compensatory mechanisms in agenesis of the corpus callosum, Neurology 18: 307.Google Scholar
  23. Saul, R. E. and Sperry, R. W., 1968, Absence of commissurotomy symptoms with agenesis of the corpus callosum, Neurology 18: 307.PubMedGoogle Scholar
  24. Sperry, R.W., 1968, Plasticity of neural maturation, Dey. Biol. Suppl. 2: 306–327.Google Scholar

Copyright information

© Plenum Press, New York 1994

Authors and Affiliations

  • Gina M. Geffen
    • 1
  • Judith Nilsson
    • 2
  • Donald A. Simpson
    • 3
    • 4
  • Malcolm A. Jeeves
    • 5
  1. 1.Cognitive Psychophysiology Laboratory Psychology Department and Clinical Studies UnitUniversity of Queensland and Queensland Health DepartmentBrisbaneAustralia
  2. 2.South Australia Head Injury ServiceJulia Farr CentreAdelaideAustralia
  3. 3.NH and MRC Road Accident Research UnitUniversity of AdelaideAdelaideAustralia
  4. 4.Department of NeurosurgeryAdelaide Children’s HospitalAdelaideAustralia
  5. 5.Psychological LaboratoryUniversity of St. AndrewsSt. Andrews, FifeScotland

Personalised recommendations